Fluoride Action Network

Abstract

Improved the general condition of chronic fluorosis but had no effect on dental fluorosis enhanced the excretion of fluorine and lowered the fluorine content of serum and bone which has been raised during fluorine intoxication; increased serum vitamin C and protected collagen as manifested by declin[e] of urinary hydroxyproline; inhibited lipid peroxidation induced by fluorosis through raising vitamin E level and glutathione conent, glutathione peroxidase and superoxide dismutase activities of blood, liver and kidney so that lipid peroxide level in these tissues was lowered; repaired liver and kidney damages of fluorotic origin revealed by the lowering of serum GPT, liver triglycerides and urine gamma-GT.