Abstract
Fluoride concentrations in maternal and cord blood were measured for the first time with a method specific for inorganic fluoride. The concentrations averaged 0.88 ?M in blood from 16 mothers and 0.68 ?M in the cord blood, with a correlation of 0.86. These results are consistent with the hypothesis that fluoride diffuses passively across the placenta. The term placenta, as previously reported, can have much higher concentrations (average 50 ?M), but the acid-stable organic fluoride averaged only 4 ?M, which is similar to the valves found in human sera.
• Supported in part by Grant No. 1-P11-GM-15190 from the National Institutes of Health.
• This paper is taken from a thesis submitted in partial fulfilment of the requirements for the Master of Science degree. (Y.-W. Shen.)
• Present address: Department of Pharmacology, College of Medicine, Chicago, Illinois.
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Environmental Fluoride 1977 by Rose & Marier
The Associate Committee on Scientific Criteria for Environmental Quality was established by the National Research Council of Canada in response to a mandate provided by the Federal Government to develop scientific guidelines for defining the quality of the environment. The concern of the NRC Associate Committee is strictly with scientific
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Association between fluoride exposure and blood pressure in children and adolescents aged 6 to19 years in the United States: NHANES, 2013–2016.
Highlights An inverse association was observed between water fluoride and childhood BP. Association between water fluoride and BP showed discrepancies in sex, age, arace. A negative association was found between plasma fluoride and BP only in other races. To examine the association between fluoride exposure and childhood blood pressure (BP), we
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The association between fluoride in water and blood pressure in children and adolescents.
Background The objective of this study was to determine the association between water and plasma fluoride and blood pressure (BP) among children and adolescents. Methods Our study population was individuals of 8–18 years in the 2013–2016 National Health and Nutrition Examination Survey. We performed a multivariable linear and logistic regression analysis to examine
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Plasma and water fluoride levels and hyperuricemia among adolescents: A cross-sectional study of a nationally representative sample of the United States for 2013–2016.
Highlights Relatively low levels of fluoride exposure in US adolescents but with wide ranges. Dose-dependent increase in prevalence of hyperuricemia with increasing fluoride levels. Significant associations between plasma and water fluoride and hyperuricemia. A positive relationship between water and plasma fluoride concentrations. Potential role of chronic fluoride exposure in
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Pharmacokinetics of 38% Silver Diamine Fluoride in Children.
Purpose: The purpose of this study was to measure serum levels and characterize the pharmacokinetics of silver and fluoride in healthy children receiving silver diamine fluoride (SDF) treatment for dental caries lesions. Methods: Children (three to 13 years old with at least one caries lesion) were recruited
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