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Absence of detrimental effects of fluoride exposure in diabetic rats.

The one histological variable on which fluoride did exert an effect in the diabetic animals was the width of the cortex in the tibia. Loss of bone mass and density are characteristic of both experimental and human diabetes and were evident in our diabetic animals in which the diaphyseal bone width was significantly less than in controls treated with 0, 5 or 15 parts/10^6 fluoride [ppm].

Analysis on TSH and intelligence level of children with dental fluorosis in a high fluoride area.

... The results of the intelligence tests show that a high level of fluoride influences children’s IQ, which is consistent with some previous data[4]. It is worth mentioning that the higher the degree of dental fluorosis, the more negative the impact on the children’s intelligence level. This is an issue which merits utmost attention. We believe that the low intelligence of children has no relation to the level of TSH. Although there are differences found in TSH values between the end

Functional state of thyroid under extended exposure to fluorides

The issue of specific effect of fluorine on the thyroid in humans remains debatable. There is no doubt, however, that cases of experimental fluorosis are characterized by specific toxicity of fluorine to the thyroid. The hypoactivity of thyroid epithelium is observed, the destructive changes in the follicular cells increasing with the increased intoxication time (1, 9). According to some authors (6, 12, 13), no specific fluorine toxicity to the thyroid is observed in fluorine-endemic areas

Circulating testosterone levels in skeletal fluorosis patients

OBJECTIVE:  The present study focuses on serum testosterone concentrations in patients with skeletal fluorosis, in order to assess the hormonal status in fluoride toxicity. METHODS:  Serum testosterones were compared for patients afflicted with skeletal fluorosis (n = 30) and healthy males consuming water containing less than 1 ppm fluoride (Control 1, n = 26) and a second category of controls (Control 2, n = 16): individuals living in the same house as the patients and consuming same water as