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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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The Abortive Lives of Modern Inhalation Anesthetics.

September 1973 | Anesthesiology | Vandam LD. | 39:259–260.
READERS of this periodical were probably intrigued when, in 1971, almost an entire issue was devoted to studies in volunteers of a new anesthetic, isoflurane (Forane), a novel and useful editorial departure. Since then, a series of reports in the Journal has cast further light on some of the more arcane properties of this heavily fluorinated ether. Why then is this well-studied drug not yet available for clinical use, while its isomer, enflurane, has been accorded official approval? How and when

Cytogenetic effect of inorganic fluorine compounds on human and animal cells in vivo and in vitro

1973 | Genetika | Voroshilin SI, Plotko EG, Gatiyatullina EZ, Giliova EA. | 9(4):115-20.
On the grounds of the results obtained during our experiments F compounds are able to produce certain changes in chromosomes from somatic cells of animals treated in vivo by them… Most of the aberrations observed in the case of bone marrow cells were chromatid-type aberrations… [W]e entertain the opinion that the main damage to chromosomes during our experiments with F compounds also took part during the S-phase… [T]hese data enable us to consider as sufficiently established the conclusion

Fluoride metabolism in uremia

1973 | Transactions of the American Society of Artifical Internal Organs | Nielsen E, Solomon N, Goodwin NJ, Siddhivarn N, Galonsky R, Taves D, Friedman EA. | 19:450-5.
Summary These data show that: 1. During a 2 year period, the chronic use of fluoridated water in patients undergoing maintenance hemodialysis was associated with a rise in serum phosphatase in 10 of 20 patients studied and an increased radiographic incidence of osteodystrophy. 2. Eight long-term hemodialysis patients manifested no radiographic evidence of osteodystrophy during their first 2 to 6 years of hemodialysis, and one of these patients currently has a negative bone survey, 9 years aft

Acute sodium fluoride poisoning.

November 13, 1972 | JAMA (The Journal of the American Medical Association) | Abukurah AR, Moser AM, Baird CL, Randall RE, Setter JG, Blanke RV. | 222(7):816-17.