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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Effects of long-term fluoride exposure are associated with oxidative biochemistry impairment and global proteomic modulation, but not genotoxicity, in parotid glands of mice.

January 27, 2022 | PLoS One | Miranda GHN, Alencar de Oliveira Lima L, Bittencourt LO, Dos Santos SM, Platini Caldas de Souza M, Nogueira LS, de Oliveira EHC, Monteiro MC, Dionizio A, Leite AL, Pessan JP, Buzalaf MAR, Lima RR. | 17(1):e0261252.
Background Fluoride has become widely used in dentistry because of its effectiveness in caries control. However, evidence indicates that excessive intake interferes with the metabolic processes of different tissues. Thus, this study aimed to investigate the effects of long-term exposure to F on the parotid salivary gland of mice, from the analysis of oxidative, proteomic and genotoxic parameters. Materials and methods The animals received deionized water containing 0, 10 or 50

The effect of community water fluoridation cessation on children’s dental health: a national experience.

January 28, 2022 | Israel Journal of Health Policy Research | Tobias G, Mordechai F, Tali C, Yaron B, Beatrice GP, Jonathan M, Harold SC. | 11:4.(Open Access)
Background Community water fluoride (CWF) is the proven cornerstone of primary dental health care promotion. In 2002 CWF was made mandatory at a national level in Israel, however a new government revoked these regulations in August 2014. "Maccabi" is the second largest national health care provider with 2.3 million members, "Maccabi-Dent", its dental branch, has 53 clinics, employing 1100 dentists. The aim of this study was to evaluate the cumulative effect on treatment rates 6 years aft

Sex-specific effects of fluoride and lead exposures on histology, antioxidant physiology, and immune system in the liver of zebrafish (Danio rerio).

January 27, 2022 | Ecotoxicology | Wang G, Wang T, Zhang X, Chen J, Feng C, Yun S, Cheng Y, Cheng F, Cao J. | [Epub ahead of print]
Affiliations College of Veterinary Medicine, Shanxi Agricultural University, Taigu, 030801, Shanxi, China Guodong Wang, Tianyu Wang, Xiulin Zhang & Jianjie Chen College of Biological and Food Engineering, Anyang Institute of Technology, Anyang, 455000, Henan, China Guodong Wang College of Food Science and Technology, Shanxi Agricultural University, Taigu, 030801, Shanxi, China Cuiping Feng, Shaojun Yun, Yanfen Cheng, Feier Cheng & Jinling Cao Correspon