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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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The distribution of fluoride of prenatal origin in the rat–a pilot study.

January 1, 1989 | Archives of Oral Biology | Chan JT, Qiu CC, Whitford GM, Weatherred JG, Clardy RK. | 34(11):885-888.
References (31) P.F. DePaola et al. A pilot study of the relationship between caries experience and surface enamel fluoride in man Archs oral Biol. (1975) R.G. Schamschula et al. Associations between fluoride concentration in successive layers of human enamel and individual dental caries experience Archs oral Biol. (1979) D.R. Taves Determination of submicromolar concentrations of fluoride in biological samples Talanta (1968) G.M. Whitford et al. Plasma an

Biphasic Functions of Sodium Fluoride (NaF) in Soft and in Hard Periodontal Tissues.

January 16, 2022 | International Journal of Molecular Sciences | Wang X, Tewari N, Sato F, Tanimoto K, Thangavelu L, Makishima M, Bhawal UK. | 23(2):962.
1. Introduction Fluoride is well known for its use in the treatment of dental caries, either systemically or topically [1]. Fluoride intake (such as in drinking water, fluoridated toothpaste, or fluoride supplements) is the cornerstone to preventing dental caries in adults and children. Fluoride prevents dental caries by slowing down the demineralization of enamel, which is caused by the interaction between dental plaque and dental hard tissues. Fluoride may inhibit tooth decay by 40–60

Possible Association Between Polymorphisms in ESR1, COL1A2, BGLAP, SPARC, VDR, and MMP2 Genes and Dental Fluorosis in a Population from an Endemic Region of West Bengal.

January 23, 2022 | Biological Trace Element Research | Chakraborty A, Pramanik S, Datta K, Goswami R, Saha D, Majumdar KK, Sikdar N. | [Epub ahead of print]
References 1. Podgorski JE, Labhasetwar P, Saha D, Berg M (2018) Prediction modeling and mapping of groundwater fluoride contamination throughout India. Environ Sci Technol 52. https://doi.org/10.1021/acs.est.8b01679 2. Del Bello L (2020) Fluorosis: an ongoing challenge for India. Lancet Planet Heal 4. https://doi.org/10.1016/S2542-5196(20)30060-7 3. Majumdar KK (2011) Health impact of supplying safe drinking water containing fluoride below permissible level on flourosis patient

Fluoride toothpastes of different concentrations for preventing dental caries.

March 4, 2019 | The Cochrane Database of Systematic Reviews | Walsh T, Worthington HV, Glenny AM, Marinho VC, Jeroncic A. | 3(3):CD007868.
Plain language summary available in English Español ????? Français Hrvatski ??? Bahasa Malaysia Polski ??????? ???? Authors' conclusions Implications for practice Overall, there does appear to be some evidence of a dose-response relationship in the caries-preventive effects of fluoride in toothpastes, with the magnitude of the caries-preventive effect estimate increasing as the distance between the lower and higher fluoride concentrati

Evaluation of fluoride release from commercially available fluoride varnishes.

October 1, 2001 | Journal of the American Dental Association | Castillo JL, Milgrom P, Kharasch E, Izutsu K, Fey M. | 132(10):P1389-1392.
References Murray JJ Winter GB Hurst CP Duraphat fluoride varnish: a 2-year clinical trial in 5-year-old children. Br Dent J. 1977; 143: 11-17 View in Article Scopus (37) PubMed Crossref Google Scholar Holm AK Effect of fluoride varnish (Duraphat) in preschool children. Community Dent Oral Epidemiol. 1979; 7: 241-245 View in Article Scopus (65) PubMed Crossref Google Scholar Petersson LG Arthursson L Ostberg