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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Protocol for a family-centered behavioral intervention to reduce early childhood caries: the MySmileBuddy program efficacy trial.

May 7, 2021 | BMC Oral Health | Lumsden CL, Edelstein BL, Basch CE, Wolf RL, Koch PA, McKeague I, Leu CS, Andrews H. | 21(1):246.
Background Although largely preventable through diet management and topical fluoride use, early childhood caries (ECC) often progresses to severity that necessitates surgical repair. Yet repair often fails to mitigate caries progression. Needed is an effective behavioral intervention to address underlying behavioral causes. Methods This randomized controlled trial will evaluate the efficacy of a behaviorally focused, family-centered intervention, the MySmileBuddy Program (MSB Program),

Impact of Chronic Sodium Fluoride Toxicity on Antioxidant Capacity, Biochemical Parameters, and Histomorphology in Cardiac, Hepatic, and Renal Tissues of Wistar Rats.

January 12, 2022 | Biological Trace Element Research | Sharma P, Verma PK, Sood S, Singh M, Verma D. | [Epub ahead of print]
References 1. Ludlow M, Luxton G, Mathew T (2007) Effects of fluoridation of community water supplies for people with chronic kidney disease. Nephrol Dial Transplant 22:2763–2767. https://doi.org/10.1093/ndt/gfm477 Article  PubMed  Google Scholar 2. Council NR (2006) Fluoride in drinking water. National Academies Press, Washington, D.C. Google Scholar 3. Ahmed KM, Bhattacharya P, Hasan MA et al (2004) Arsenic enrichment in groundwater of the alluvial aquifers in

Physiological effects induced by aluminium and fluoride stress in tall fescue (Festuca arundinacea Schreb).

January 15, 2022 | Ecotoxicology and Environmental Safety | Fan J, Chen K, Xu J, Abm K, Chen Y, Chen L, Yan X. | 231:113192.
1. Introduction Aluminium (Al) is a major element of soil, and it turns into toxic forms when expose to acidic condition. Al3+ ions are released from clay minerals in acidic soils, which in turn inhibit root growth and reduce crop yields. It is reported that approximately 40–50% potentially arable lands are acidic in the world (Von Uexküll and Mutert, 1995). Root is very sensitive to Al3+ toxicity and root meristem is the primary site of Al toxicity (Ryan et al., 1993). Root growth in wheat

NHS dental activity: a population marker for the effectiveness of community water fluoridation in children in England.

January 14, 2022 | British Dental Journal | Henein C, Landes D. | [Epub ahead of print]
References 1. Selwitz R H, Ismail A I, Pitts N B. Dental caries. Lancet 2007; DOI: 10.1016/S0140-6736(07)60031-2. 2. Scarpelli A C, Paiva S M, Viegas C M, Carvalho A C, Ferreira F M, Pordeus I A. Oral health-related quality of life among Brazilian preschool children. Community Dent Oral Epidemiol 2013; 41: 336-344. 3. Martins-Júnior P A, Vieira-Andrade R G, Corrêa-Faria P, Oliveira-Ferreira F, Marques L S, Ramos-Jorge M L. Impact of early childhood caries on the oral health-re