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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Equine dental and skeletal fluorosis induced by well water consumption.

October 14, 2020 | Journal of Veterinary Diagnostic Investigation | Kelly LH, Uzal FA, Poppenga RH, Kinde H, Hill AE, Wilson D, Webb BT. |
References 1. Baker, GJ. Some aspects of equine dental disease. Equine Vet J 1970;2:105–110. Google Scholar | Crossref 2. Baumhammer, A , et al. Remodeling of alveolar bone. J Periodontol 1965;36:439–442. Google Scholar | Crossref | Medline 3. Beck, JD. Fluorine poisoning in a horse. J Am Vet Med Assoc 1946;109:59. Google Scholar | Medline 4. Buzalaf, MAR, Whitford, GM. Fluoride metabolism. In: Buzalaf, MAR , ed. Fluoride and the Oral

Slightly Elevated Serum Ionic Fluoride Levels Inhibit Insulin Secretion and Increase Glucose Levels in a General Japanese Population: a Cross-sectional Study.

October 8, 2020. | Biological Trace Element Research | Itai K, Onoda T, Nohara M, Kuribayashi T, Tanno K, Ohsawa M, Mori M, Okayama A. | [Epub ahead of print]
References 1.  Whitford GM (1996) The metabolism and toxicity of fluoride. Monogr Oral Sci 16. Rev 2. 1–153 2.  Tsunoda N, Sakurai S, Tsunoda H (1986) Gastrointestinal absorption of fluoride in humans—a comparative study of NaF and CaF2. In: Humio T and Ming-Ho Yu (ed) Fluoride research 1985, studies in environmental science 27. Elsevier, Amsterdam, pp389–394 3.  Everett ET (2011) Fluoride's effects on the formation of teeth and bones, and the influence of genetics. J D

The effect of vitamin E and selenium combination in repairing fluoride-induced DNA damage to NRK-52E cells.

October 6, 2020 | Molecular Biology Reports | Yuksek V, Cetin S, Usta A. | [Epub ahead of print]
References Anuradha CD, Kanno S, Hirano S (2001) Oxidative damage to mitochondria is a preliminary step to caspase-3 activation in fluoride-induced apoptosis in HL-60 cells. Free Radical Biol Med 1:367–373 Article  Google Scholar Bai C, Chen T, Cui Y, Gong T, Peng X, Cui HM (2010) Effect of high fluorine on the cell cycle and apoptosis of renal cells in chickens. Biol Trace Elem Res 138:173–80 CAS  PubMed  Article  Google Scholar Barbier O, Arreola-Mendoz

Effects of Fluoride Long-Term Exposure over the Cerebellum: Global Proteomic Profile, Oxidative Biochemistry, Cell Density, and Motor Behavior Evaluation.

October 2, 2020 | International Journal of Molecular Sciences | Lopes GO, Ferreira MKM, Davis L, Bittencourt LO, Aragao WAB, Dionizio A, Buzalaf MAR, Crespo-Lopez ME, Maia CSF, Lima RR. | 21(19):7297.
Funding This study was financed by the National Council for Scientific and Technological Development (CNPq) from Brazilian Ministry of Science, Technology, Innovation and Communications (MCTI) process number: 435093/2018-5 approved by R.L. L.B. and A.D. received CNPq and FAPESP scholarships, respectively. M.B., M.E.C.-L. and C.M. thanks for CNPq fellowship. The APC was funded by Pró-Reitoria de Pesquisa e Pós-graduação da Universidade Federal do Pará (PROPESP-UFPA). Acknowledg

Investigation of the genotoxic effects of fluoride on a bone tissue model .

October 1, 2020 | Toxicological Research | Volobaev VP, Kalyuzhnaya EE, Schetnikova EA, Korotkova AD, Naik AA, Bach SN, Prosekov AY, Larionov AV. | 36:337–342.
References Lav KH, Baylink DJ (1998) Molecular mechanism of action of fluoride on bone cells. J Bone Miner Res 13:1660–1667 Article  Google Scholar Perumal E, Paul V, Govindarajan V, Panneerselvam L (2013) A brief review on experimental fluorosis. Toxicol Lett 223:236–251 CAS  Article  Google Scholar Purohit SD, Gupta RC, Mathur AK, Gupta N, Jeswani ID, Choudhary VK (1999) Experimental pulmonary fluorosis. Indian J Chest Dis Allied Sci 41:27–34 CAS  Pu

A randomised oral fluoride retention study comparing intra-oral kinetics of fluoride-containing dentifrices before and after dietary acid exposure.

September 2020 | Archives of Oral Biology | Gary Burnett, Marc Nehme, Charles Parkinson, Ritu Karwal, Thomas Badrock, Gavin Vaughan Thomas, Peter Hall. | 119:104891.
Acknowledgments Editorial assistance with the preparation of manuscript drafts was provided by Juliette Allport, Leading Edge, and Eleanor Roberts, Beeline Science Communications Ltd., both funded by GSK Consumer Healthcare [GlaxoSmithKline] *Read full text online at https://www.sciencedirect.com/science/article/pii/S0003996920302697#!