Tag: Glial cells
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Interplay of glia activation and oxidative stress formation in fluoride and aluminium exposure.
A role of fluoride on free radical generation and oxidative stress in BV-2 microglia cells.
In conclusion, a main finding of this study was that microglia BV-2 cells were activated by fluoride, and the increase of ROS and RNS in microglia was associated with the activation of microglia. The novelty of this work is related to the active role of microglia treated with fluoride. We provided new evidence from in […]
Distribution and different activation of adenylate cyclase by NaF and of guanylate cyclase by NaN3 in neuronal and glial cells separated from rat cerebral cortex.
JNK and NADPH oxidase involved in fluoride-induced oxidative stress in BV-2 microglia cells.
Abstract Excessive fluoride may cause central nervous system (CNS) dysfunction, and oxidative stress is a recognized mode of action of fluoride toxicity. In CNS, activated microglial cells can release more reactive oxygen species (ROS), and NADPH oxidase (NOX) is the major enzyme for the production of extracellular superoxide in microglia. ROS have been characterized as […]