Excerpt:
Summary and Conclusions
1. Results of surveys made in Oklahoma Panhandle on Chronic Fluorine Intoxication was stated, the endemic areas located, the mottled enamel index derived, the fluorine content of the water supply of the different areas given along with the depth of the wells, along with the findings on physical examinations of those afflicted with this condition.
2. That there is evidence which indicates that there is a definite relation between chronic fluorine poisoning as detected by mottling of the enamel and child development, particularly as to predisposition to developing underweight, poor posture, rickets and orthopedic conditions.
3. Possible methods of controlling and preventing this condition were suggested.
4. Dental caries, gingivitis, malocclusion, beginning phorrhea and poor oral hygiene incidence in mottled enamel is high.
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Vitamin D deficiency, rickets, and fluorosis in India
Data on the vitamin D status of the populations in a tropical country like India have seldom been documented. Vitamin D deficiency is presumed to be rare. Population studied by the author and others in the country has proved otherwise. Studies were carried out to document the dietary habits, serum
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Genu valgum and osteoporosis in an area of endemic fluorosis
Twenty-four male patients with genu valgum deformity drawn from an area of endemic fluorosis in Andhra Pradesh, India, were investigated clinically, radiologically, and biochemically. All had evidence of spinal osteosclerosis along with extensive osteoporotic changes in the bones of the extremities. Levels of serum calcium, phosphorus, and alkaline-phosphatase activity were
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Nutritional bone disease in Indian population
Syndromes of bone disease and deformities consequent to disorders of nutrition, bone and mineral metabolism constitute a serious national health problem. The studies on this subject are scanty. Data on nutritional bone disease are described and discussed. We had surveyed 337.68 million population residing in 0.39 million villages in 22
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Endemic chronic fluoride toxicity and dietary calcium deficiency interaction syndromes of metabolic bone disease and deformities in India: year 2000
Epidemiological studies during 1963-1997 were conducted in 45,725 children exposed to high intake of endemic fluoride in the drinking water since their birth. Children with adequate (dietary calcium > 800 mg/d) and inadequate (dietary calcium < 300 mg/d) calcium nutrition and with comparable intakes of fluoride (mean 9.5 +/- 1.9
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Experimental chronic fluorine intoxication: Effect on bones and teeth
Chronic fluorine intoxication of puppies produced extensive systemic changes of the bones and developing teeth. The intensity depended upon the age of the animal, the dose, and the duration of the administration of sodium fluoride. In puppies fed exclusively the milk of their fluorine-poisoned mother, changes of the bones were
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