Abstract
Six cases of urticaria are reported in which trace quantities of fluoride proved to have played a major etiological role. The causative relationship was established by blindfold tests, by the history and by the concomittant symptomatology. Following an oral test dose of fluoride given to five of the six cases a significantly lower urinary F-output was noted than in normal controls.
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Allergic reactions from fluorides
In a discussion of drug allergy it is necessary to distinguish between intolerance and allergy to drugs. One represents intoxication, the other is characterized by wheal formation, eosinophilia and other features of an allergic reaction. Gastric irritation, for instance, or acne from iodides or bromides represent intolerance to these drugs
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Symptoms experienced during periods of actual and supposed water fluoridation
Fluoridation of water is a controversial measure because of the suspicion that it has harmful effects on health. Opinions differ as to the reality of these fears. In Kuopio, after distressing disputes over the fluoridation issue, the City Council decided to stop fluoridation at the end of 1992. In fact,
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Fluoride toothpaste: a cause of acne-like eruptions
I feel that I should share with my colleagues in dermatology an observation relative to the treatment of problem acne. All of us have the adult female acne patient who has closed comedonal or papular acne extending from the corner of the mouth to the chin area, sometimes in a
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Prenatal and postnatal ingestion of fluorides: fourteen years of investigation -- final report*.
SUMMARY Data is presented showing that fluoride ingested by gravid women enters the maternal circulation, is stored in the placenta and passes through the placental barrier to enter the foetal blood supply. Evidence is presented that the fluoride in the foetal blood supply affects the developing teeth to make them more resistant
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Irritant contact dermatitis due to ammonium bifluoride in two infant twins
Ammonium bifluoride is one of the most corrosive acids that may produce severe chemical burns when in contact with skin. This hazardous chemical is widely used in household products. We report two pediatric cases of irritant contact dermatitis after exposure to a rust remover, which contained ammonium bifluoride.
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Mayo Clinic: Fluoridation & Bone Disease in Renal Patients
The available evidence suggests that some patients wtih long-term renal failure are being affected by drinking water with as little as 2 ppm fluoride. The finding of adverse effects in patients drinking water with 2 ppm of fluoride suggests that a few similar cases may be found in patients imbibing 1 ppm, especially if large volumes are consumed, or in heavy tea drinkers. The finding of adverse effects in patients drinking water with 2 ppm of fluoride suggests that a few similar cases may be found in patients imbibing 1 ppm, especially if large volumes are consumed, or in heavy tea drinkers and if fluoride is indeed the cause. It would seem prudent, therefore, to monitor the fluoride intake of patients with renal failure living in high fluoride areas.
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Allergic Reactions from Fluorides
Six cases are described with allergic manifestations from fluorides. The symptoms were reproduced by administering an aqueous fluoride solution either by ingestion, injection or local application. Control tests had no such effect. The patients had no way of knowing which solution contained fluoride.
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Fluoride Dentrifice and Stomatitis
Statistical data of 133 patients who have been using fluoride dental cream or powder have been presented. Each has developed intraoral ulcerative lesions. Many have been treated for other complaints without clearance of the lesions. Age is not significant. Repeated insults with the fluoride dentrifices produced increasingly severe excoriations. There seems to be nothing specific about the lesions to differentiate them from other diseases of an oral nature.
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Fluoride & Perioral Dermatitis
Perioral dermatitis (PD) is a common rosacea-like dermatitis that was never reported prior to the mid-fifties. Although it can affect both sexes and all ages, most patients are women ages 20-50 years. Patients with PD frequently report a pre-existing tendency to blush. This disease is most likely multifactorial in origin, and fluoride preparations in dentrifices probably have played a role as precipitator.
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Fluoridation of drinking water and chronic kidney disease: Absence of evidence is not evidence of absence
A fairly substantial body of research indicates that patients with chronic renal insufficiency are at an increased risk of chronic fluoride toxicity. Patients with reduced glomerular filtration rates have a decreased ability to excrete fluoride in the urine. These patients may develop skeletal fluorosis even at 1 ppm fluoride in the drinking water.
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