Extract
Like the skin and its appendages, the teeth, nails and hair, so also other tissues of ectodermal origin are here shown to be affected by fluorine. The action of fluorine consists in lowering the level of the calcium in the blood and tissues. The epithelia of the mouth and the salivary glands, of the nasopharynx, the conjunctivae and the lachrymal glands may be affected. Signs and symptoms are thus produced which are closely similar to those usually attributed primarily to infection. It is suggested that an infection accompanying chronic fluorine poisoning is of a secondary nature, and that it is brought about by the loss of calcium in the body.
References
-
Ainsworth, N. J. (1933). Brit. Dent. J. 55, 233. Google ScholarBroekema, J. H. (1933). Acta derm.-venereol., Stockh., 14, 113. Google ScholarDean, H. T. (1936). J. Amer. Med. Ass. 107, 1269. CrossRef | Google ScholarDean, H. T. & Elvove, E. (1936). Amer. J. Publ. Hlth, 26, 567. CrossRef | Google ScholarErdheim, J. (1906). Mitt. Grenzgeb. Med. Chir. 16, 632. Google ScholarFriedmann, M. (1921). Arch. Derm. Syph., Berlin, 135, 161. CrossRef | Google ScholarGaud, Charnot & Langlais, (1935). Odontologie, 73, 188. Google ScholarGilford, H. (1904). Practitioner, 73, 188. Google ScholarGoeckermann, W. H. (1920). Arch. Derm. Syph., Chicago, 1, 396. CrossRef | Google ScholarHill, A. M. (1933). Arch. Derm. Syph., Chicago, 28, 66. CrossRef | Google ScholarJacobsen, A. W. (1928). J. Amer. Med. Ass. 90, 686. CrossRef | Google ScholarJosephson, E. M. & Lerner, C. (1934). Arch. Derm. Syph., Chicago, 29, 703. CrossRef | Google ScholarKaznelson, P., Reimann, F. & Weiner, W. (1929). Klin. Wschr. 81, 1071. CrossRef | Google ScholarLachmann, A. (1941). Acta Med. Scand., Suppl. 121. Google ScholarMcEwen, E. L. (1916). J. Cutan. Dis. 34, 15. Google ScholarMacKee, G. M. & Andrews, G. C. (1924). Arch. Derm. Syph., Chicago, 10, 673. CrossRef | Google ScholarMendes da Costa, S. & Van der Valk, J. W. (1919). Urol. Cutan. Rev. 23, 159. Google ScholarNicolle, G. & Halipré, A. (1895). Ann. Derm. Syph., Paris, 6, 675, 804. Google ScholarSpira, L. (1928). Franco-Brit. Med. Rev. 5, 1, 61. Google ScholarSpira, L. (1933). The Clinical Aspect of Chronic Poisoning by Aluminium and its Alloys. London. Google ScholarSpira, L. (1942 a). Edinb. Med. J. 49, 707. Google ScholarSpira, L. (1942 b). J. Hyg., Camb., 42, 500. CrossRef | Google ScholarSpira, L. (1943 a). J. Hyg., Camb., 43, 69. CrossRef | Google ScholarSpira, L. (1943 b). To be published. Google ScholarSpira, L. (1943 c). Edinb. Med. J. 50, 237. Google ScholarThurnam, J. (1848). Proc. Roy. Med. Chir. Soc. 31, 71. CrossRef | Google ScholarWeech, A. A. (1929). Amer. J. Dis. Child. 37, 766. CrossRef | Google ScholarWenner, W. F. (1931). J. Lab. Clin. Med. 16, 341. Google Scholar
-
-
[Effects of excess fluoride on bone turnover under conditions of diet with different calcium contents].
OBJECTIVE: To study the effects of excess fluoride on bone turnover under conditions of diet containing different amount of calcium. METHODS: The experiment was performed on rats raised on a balanced diet with adequate calcium or a monotonous diet with low calcium and given amount of fluoride in their drinking water
-
Calcium deficiency in fluoride-treated osteoporotic patients despite calcium supplementation
To test the hypothesis that the osteogenic response to fluoride can increase the skeletal requirement for calcium, resulting in a general state of calcium deficiency and secondary hyperparathyroidism, we assessed calcium deficiency, spinal bone density, by quantitative computed tomography, and serum PTH in three groups of osteoporotic subjects. Two of
-
Endemic chronic fluoride toxicity and dietary calcium deficiency interaction syndromes of metabolic bone disease and deformities in India: year 2000
Epidemiological studies during 1963-1997 were conducted in 45,725 children exposed to high intake of endemic fluoride in the drinking water since their birth. Children with adequate (dietary calcium > 800 mg/d) and inadequate (dietary calcium < 300 mg/d) calcium nutrition and with comparable intakes of fluoride (mean 9.5 +/- 1.9
-
The association of fluoride in drinking water with serum calcium, vitamin D and parathyroid hormone in pregnant women and newborn infants.
Background: Chronic exposure to fluoride in drinking water causes an increase in plasma fluoride levels that is related to a reduction in calcium transport across the renal tubule endoplasmic reticulum and plasma membrane. In the present study, it was hypothesised that varying levels of fluoride present in drinking
-
The effects of fluoride and low calcium on the physical properties of the rat femur
The effect of fluoride on the physical properties of bone was investi- gated with the aid of an Instron materials tester. Two groups of weanling female rats, one on an adequate (0.6% ) calcium diet and the other on a low (0.1%) diet were given the following dosage levels of
Related Studies :
-
-
-
Nutrient Deficiencies Enhance Fluoride Toxicity
It has been known since the 1930s that poor nutrition enhances the toxicity of fluoride. As discussed below, nutrient deficiencies have been specifically linked to increased susceptibility to fluoride-induced tooth damage (dental fluorosis), bone damage (osteomalacia), neurotoxicity (reduced intelligence), and mutagenicity. The nutrients of primary importance appear to be calcium,
-
Unheeded Warnings: Government Health Authorities Ignore Fluoride Risk for Kidney Patients
Despite the well known fact that individuals with kidney disease are at much higher risk of fluoride toxicity than the general population, there has yet to be any attempt in the United States, or any other country that practices mass-scale water fluoridation to determine the prevalence of fluoride-related effects (e.g.,
-
Mayo Clinic: Fluoridation & Bone Disease in Renal Patients
The available evidence suggests that some patients wtih long-term renal failure are being affected by drinking water with as little as 2 ppm fluoride. The finding of adverse effects in patients drinking water with 2 ppm of fluoride suggests that a few similar cases may be found in patients imbibing 1 ppm, especially if large volumes are consumed, or in heavy tea drinkers. The finding of adverse effects in patients drinking water with 2 ppm of fluoride suggests that a few similar cases may be found in patients imbibing 1 ppm, especially if large volumes are consumed, or in heavy tea drinkers and if fluoride is indeed the cause. It would seem prudent, therefore, to monitor the fluoride intake of patients with renal failure living in high fluoride areas.
-
Case Reports of Hypersensitivity to Ingested Fluorides
In the 1950s, the renowned allergist George Waldbott discovered that some individuals are hypersensitive to ingested fluoride. In a series of case reports and double-blind studies, Waldbott and other doctors found relatively small doses of ingested fluoride, including the consumption of fluoridated water, could induce side effects that would quickly
-
Fluoride Dentrifice and Stomatitis
Statistical data of 133 patients who have been using fluoride dental cream or powder have been presented. Each has developed intraoral ulcerative lesions. Many have been treated for other complaints without clearance of the lesions. Age is not significant. Repeated insults with the fluoride dentrifices produced increasingly severe excoriations. There seems to be nothing specific about the lesions to differentiate them from other diseases of an oral nature.
Related FAN Content :
-