Abstract

Effects of fluoride (F) on electrocardiogram (ECG) values were determined in ten healthy adult male New Zealand white rabbits. After the initial ECG values were measured, the rabbits were administered 20 mg NaF/kg body weight by oral intubation for two months, and the new ECG values were determined. There was a significant (p<0.001) decrease in the R-R interval (duration between the peaks of two consecutive R waves of ECG) and P-R interval (duration from the starting of P wave to the starting of QRS complex in ECG), while significant (p<0.001) increases in the mean heart rate and corrected QT intervals were observed compared to the initial baseline values. The results indicate that F adversely affects the ECG in male rabbits.

• Related Studies :

  • [Hydrofluoric acid injury analysis on the health of workers].

    Objective: To analyze the damage caused by hydrofluoric acid to the health of operating workers and to explore health monitoring indicators. Method: Occupational health examinations were carried out on 536 hydrofluoric acid operating workers from the etching process at a certain factory, and 256 persons in the control group. Results: Among the

  • Effects of chronic fluorosis on electrocardiogram in sheep

    This study was carried out to evaluate the effects of chronic fluorosis by means of the electrocardiograms in sheep. Ten sheep with fluorosis living around a volcanic mountain (Tendürek Mount) in East Anatolia in Turkey and 10 healthy sheep were used. Leads I, II, III, aVR, aVL, aVF, V2, V4,

  • Electrocardiographic evaluation in patients with endemic fluorosis without clinically evident heart disease

    Objective: This study was carried out to analyse the electrocardiogram (ECG) in patients with endemic fluorosis. Methods: Fifty six patients with endemic fluorosis and 44 age, sex and body mass index (BMI) matched healthy controls with normal fluoride intake underwent standart 12-lead ECG, urine fluoride level and serum sodium, potassium,

  • Study on the cardiovascular system damage in skeletal fluorosis patients

    Objective   To understand the damage to the cardiovascular systems of patients with different degrees of skeletal fluorosis after stopping fluorine exposure. Methods   65 patients with mild, moderate and severe skeletal fluorosis and 23 subjects without skeletal fluorosis as the control group were selected for detailed inquiry of cardiovascular disease history,

  • Observations on electrocardiograms in a population living in a region with coal-burning-borne endemic fluorosis after comprehensive controls

    Objective: To observe the electrocardiogram (ECG) changes in the population living in the region with coal-burning-borne endemic fluorosis (EF for short) after comprehensive controls. Methods: People living in a region with coal-burning-borne EF in Bijie City of Guizhou Province were selected and then divided into 4 groups according to the

• Related FAN Content :

  • Fluoride & Arteriosclerosis

    Healthy arteries are flexible and elastic, allowing efficient transfer of blood and nutrients from the heart to the rest of the body. Arteriosclerosis refers to a stiffening of the arteries, including loss of elasticity. This is a slow, progressive disease that may begin early in life from damage to the

  • Fluoride & Electrocardiogram Abnormalities

    An electrocardiogram (ECG) is a diagnostic test that measures the electrical activity of the heart. An ECG can reveal heart rate, heart rhythym (i.e. steady or irregular), and the strength and timing of the heart’s natural electrical signals. ECGs are described in terms of “waves” (e.g. amplitude and duration). Problems

  • Fluoride & Arterial Calcification

    The major change involved with cardiovascular disease is development of atherosclerosis in critical arteries, which is partially characterized by vascular calcification. The level of coronary artery calcification is thought to be the most important indicator of future cardiovascular events. Increased arterial calcifications have frequently been reported in those with skeletal fluorosis

  • Fluoride & Myocardial Damage

    Structural damage to the heart resulting from fluoride toxicity has been observed in numerous human and animal studies. The general features of this damage include cloudy swelling, vacuolization or vacuolar degeneration, hemorrhages, interstitial edema, fibrous necrosis, dissolution of nuclei, and thickening of the vessel walls in the heart muscle (Basha

  • Fluoride, Blood Pressure and Hypertension

    Individuals with blood pressure readings that exceed 140/90 are considered hypertensive. Hypertension can increase the risk of stroke, heart attack, heart failure, aortic aneurysms, and peripheral arterial disease. An association between increased fluoride in ground water and increased prevalence of hypertension has been observed, especially among adult males (Amini et