Abstract
No abstract available
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Epidemiological study of goitre in endemic fluorosis district of Gujarat
Soft tissue fluoride toxicity is well established. Several animal and human studies of the effect of fluoride on the thyroid gland have shown conflicting results. Endemic fluorosis and goitre are widespread in India with considerable overlapping in different geographical zones. We examined 22,276 individuals for presence of goitre and dental
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Endemic goitre in the absence of iodine deficiency in schoolchildren of the Northern Cape Province of South Africa
OBJECTIVE: The study was undertaken to investigate whether endemic goitre still exists in the Northern Cape Province of South Africa more than 55 years after it was reported and, if so, whether iodine deficiency, or fluoride in the drinking water, is linked to the goitres. DESIGN: Cross-sectional study of children in three pairs
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The effects of high levels of fluoride and iodine on intellectual ability and the metabolism of fluoride and iodine.
The authors carried out a study on the intellectual abilities and fluoride/iodine metabolism of children living in a high fluoride-high iodine area. Among the results: the percentage of the general population living in this fluoride/iodine-contaminated region that suffered from goiter (clinical thyroid enlargement) was 3.8%, the rate of children already showing some thyroid
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Studies of the effect of salt iodization on endemic goiter in Taiwan. IV. A survey of drinking-water in relation to endemic goiter.
No abstract available
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Prevalence and manifestations of water-born fluorosis among schoolchildren in Kaiwara village of India: a preliminary study
Background: Fluorosis is an endemic condition with prevalence in 19 states and union territories in India. It is an urgent task to survey the fluorosis-related problems in these regions. Objective: To study the clinical manifestations of water-born fluorosis among schoolchildren in Kaiwara village of India. Methods: A cross-sectional study was conducted in
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Fluoride & Goiter
Goitre (aka goiter) is an enlargement of the thyroid gland that in some cases can produce visible swelling in the neck. The main cause of goitre is iodine deficiency. Goitre can also be caused by other things, including hypothyroidism and substances that cause goitre (goitrogens). Since as far back as the
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Fluorine in the Aetiology of Endemic Goitre
The distribution of endemic goitre in the Punjab and in England is related to the geological distribution of fluorine and to the distribution of human dental fluorosis (mottled enamel). Inquiry showed the presence of dental fluorosis among school-children in two areas of Somerset where two previous observers had recorded a high incidence of goitre, and the absence of dental fluorosis in an adjoining area selected as control where endemic goitre was absent.
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The Relationship Between Fluoride Exposure & Goitre in South Africa
As a general rule simple goitre, irrespective of the cause, can be very, or fairly, satisfactorily combated by an adequate increase in man's daily iodine intake, except when the enlargement of the gland is due to the ingestion of excessive amounts of fluorine. The only correct solution to fluorine-induced endemic goitre is the removal of this element from the drinking water.
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Fluoride, Water Hardness, and Endemic Goitre
Variations in goitre prevalence were found to correlate closely with the fluoride content (p=0-74; P<0-01) and with the hardness (p=0.77; P<0-01) of the water in each village. The effects of fluoride and water hardness seem to be independent.
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Fluoride's Impact on Thyroid Hormones
Up through the 1950s, doctors in Europe and South America prescribed fluoride for this purpose in patients with hyperthyroidism. (Merck Index 1968). Fluoride was selected as a thyroid suppressant based on findings dating back to the mid-19th century that fluoride is a goitrogen (a substance that can cause goiter). When used as
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