Thursday, April 30th, 2015

Small molecule fluoride toxicity agonists

INTRODUCTION Although fluoride is commonly added to oral hygiene products to increase the strength of tooth enamel, it also has substantial anti-bacterial effects (Barbier et al., 2010; Li, 2003). For example, when in complex with a divalent metal ion and ADP, fluoride forms a nonfunctional mimic of ATP that can inhibit enolase (Curran et al., […]