Thyroid function in endemic hydrofluorosis in Sicily.

In pursuit of former observations on hydrofluorosis the authors conducted an investigation concerning the incidence of goiter and the function of the thyroid gland in subjects with hydrofluorosis from Aquaviva Platani, a large endemic center of Sicily. To evaluate thyroid function, radio-iodine uptake and the conversion index (PBI) with 131I

[Effects of fluoride on thyroid structure in chicks].

Objective: To investigate the effects of fluoride on thyroid structure in chicks. Methods: 250 one day chicks were randomly divided into 5 groups, 50 for each. Group I was the control, and other four groups, group II, III, IV, V were fed the diets containing 500, 1,000, 1,500, 2,000 mg/kg of

[Effect of different fluoride and iodine concentration in drinking water on children's dental fluorosis and thyroid function].

Objective: To investigate the effect of different concentrations of fluoride and iodine in drinking water on children's dental fluorosis and thyroid function. Methods: According to different concentration of fluoride and iodine in drinking water, four villages in two counties of Henan province were classified as high fluoride and iodine, high fluoride,

Assessment of iodine status in children, adults, pregnant women and lactating women in iodine-replete areas of China

BACKGROUND: Iodine deficiency disorders (IDD) are widespread in China. Presently, IDD have been put under control by Universal Salt Iodisation (USI) in China; however, there is a lack of evidence on whether the iodine status in adults, pregnant women and lactating women is optimal. This study was therefore conducted to assess

Goitre and Fluorosis in Kenya

Fluorine in the Aetiology of Endemic Goitre

The distribution of endemic goitre in the Punjab and in England is related to the geological distribution of fluorine and to the distribution of human dental fluorosis (mottled enamel). Inquiry showed the presence of dental fluorosis among school-children in two areas of Somerset where two previous observers had recorded a high incidence of goitre, and the absence of dental fluorosis in an adjoining area selected as control where endemic goitre was absent.

Fluoride, Water Hardness, and Endemic Goitre

Variations in goitre prevalence were found to correlate closely with the fluoride content (p=0-74; P<0-01) and with the hardness (p=0.77; P<0-01) of the water in each village. The effects of fluoride and water hardness seem to be independent.

The Relationship Between Fluoride Exposure & Goitre in South Africa

As a general rule simple goitre, irrespective of the cause, can be very, or fairly, satisfactorily combated by an adequate increase in man's daily iodine intake, except when the enlargement of the gland is due to the ingestion of excessive amounts of fluorine. The only correct solution to fluorine-induced endemic goitre is the removal of this element from the drinking water.

Fluoride & Goiter

Goitre (aka goiter) is an enlargement of the thyroid gland that in some cases can produce visible swelling in the neck. The main cause of goitre is iodine deficiency. Goitre can also be caused by other things, including hypothyroidism and substances that cause goitre (goitrogens). Since as far back as the

NRC (2006): Fluoride's Impact on the Thyroid Gland

Several lines of information indicate an effect of fluoride exposure on thyroid function. It is difficult to predict exactly what effects on thyroid function are likely at what concentration of fluoride exposure and under what circumstances.