Abstract
As fluoride inhibits Glycolysis we conducted a preliminary study to analyse the effect of fluoride on blood glucose in the individuals of endemic fluorosis area .
The study was conducted to correlate the serum fluoride with blood glucose levels in a population living in endemic fluorosis area
The present study included serum samples of 104 male and female of various age groups 20 – 70 yrs. The patients had attended OPD of Kamineni Institute of medical sciences hospital and advised for RBS. Blood glucose was estimated by hexokinase method using Dade Behring Dimension AR. Serum fluoride was estimated using ion selective electrode ECOSAN statistical analysis was done by using SPSS software.
Based on our findings, we made 3 different groups .Group-I comprised of both having increased RBS and fluoride levels(Males 4%, Females 5%) Group II comprised of patients having increased serum fluoride levels with normo glycemia (Males 44% Females 44%) and Group III consisted of patients having hyper glycemia and normal fluoride ( Males 8% Females 1%).Results obtained were compared between groups I,II,III.
There was no significant correlation between serum fluoride and hyper glycemia in endemic fluorosis area. This could be due to less sample number. None the less we are still continuing with the study.
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Physiologic and metabolic benefits of formulated diets and mangifera indica in fluoride toxicity
Fluorosis is a major health problem affecting normal physiological and metabolic functions in people living in endemic fluoride areas. The present work was aimed at investigating the role of basal, high carbohydrate low protein (HCLP) and high protein low carbohydrate (HPLC) diets and Mangifera indica fruit powder as a food
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Reversible impairment of glucose tolerance in patients with endemic fluorosis. Fluoride Collaborative Study Group.
Endemic fluorosis is a condition resulting from prolonged ingestion of drinking water which contains excess fluoride. Studies on rats have suggested that fluoride toxicity may produce glucose intolerance and abnormalities in insulin secretion. We studied glucose and insulin profiles following an oral glucose load in patients with endemic fluorosis. Twenty-five
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Mathematical model of glucose-insulin homeostasis in healthy rats.
According to the World Health Organization there are over 220 million people in the world with diabetes and 3.4 million people died in 2004 as a consequence of this pathology. Development of an artificial pancreas would allow to restore control of blood glucose by coupling an infusion pump to a
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[Changes in bone mass and in glucose homeostasis in subjects with high spontaneous fluoride intake]
This paper reports metabolic data of 24 women and two men, 44-66 years old, ex-residents in an area of endemic fluorosis close to Bahía Blanca city. Fasting fluoremias of these subjects (0.5 to 9.2 microM) and daily urinary fluoride excretion (> 60 mumoles/day) are characteristics of zones with endemic fluorosis.
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Fundamental and applied studies on transport and metabolism of electrolytes and glucose--aim to contact with molecular biology. [Article in Japanese]
The authors' research focuses on polyuria, natriuresis, glucosuria, glycemia, and renal calcification in occupational lead poisoning and endemic fluorosis. Changes in electrolyte mobilization and in glucose metabolism and transport following the administration of lead compounds or fluoride were examined to elucidate these mechanisms. The results suggest fundamental approaches to the
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Fluoride & Insulin
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Fluoride & Impaired Glucose Tolerance
The proper regulation of blood glucose levels is essential to good health. When the body's ability to regulate blood glucose levels falters, as occurs in diabetes mellitus, chronic elevated glucose levels (hyperglycemia) can lead to serious complications. These consequences include damage to the kidneys, nervous system, cardiovascular system, retina, legs
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Fluoridated Water Causes Severe Dental Fluorosis in Children with Diabetes Insipidus
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NRC (2006): Fluoride's Effect on Glucose Metabolism
This section on Diabetes includes: • Fluoride & Impaired Glucose Tolerance • Fluoride & Insulin • Fluoride Sensitivity Among Diabetics • Fluoridated Water Causes Severe Dental Fluorosis in Children with Diabetes Insipidus • NRC (2006): Fluoride’s Effect on Glucose Metabolism The following discussion is from pages 258-260 of the NRC’s report’s “Fluoride in Drinking Water: A Scientific
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