Abstract
Changes in skin electric potential following immune challenge provide a sensitive measure of the intensity of the allergic challenge. In guinea-pigs sensitised to Sodium Fluoride, Fluoridation Mains Tap Water, or Ovalbumen with Sodium Fluoride, and then challenged with one part in one million Sodium Fluoride, significant allergic responses were produced. Ovalbumen alone caused an allergic response only after a second challenge. Purified water did not result in any immune response. It is concluded that Fluoridated Mains Tap Water is capable of causing an allergic response similar to that produced by Sodium Fluoride alone, and that Ovalbumen potentiates the immune response to Sodium Fluoride.
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Fluoride intoxication from drinking water (a report of 52 cases)
In previous publications, cases of incipient fluorine 1) poisoning from drinking artificially fluoridated water at the 1 ppm concentration were reported. A specific disease pattern could be discerned closely tallying with what has b??n observed in industrial poisoning from fluorine intake at higher levels. There are three groups of symptoms: 1. Those
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Contact dermatitis and stomatitis due to amine fluoride
Case Report For prevention of dental caries, a 17-year-old boy had intermittently used a gel containing different fluoride compounds over a period of 2 years. In the last 2 months, 1 to 2 days after application, he had developed itchy perioral erythematous papules and plaques, with vesicles of the oral mucosa.
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Perioral dermatitis
Since its description in 1957 by Frumess and Lewis (1) as a "light-sensitive seborrheid," perioral dermatitis (PD) has been a perplexing entity. It characteristically presents as a chronic eruption consisting of papules and pustules that develop on irregular areas of erythema and edema. the eruption is most prominent in the
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Allergic reactions from fluorides
In a discussion of drug allergy it is necessary to distinguish between intolerance and allergy to drugs. One represents intoxication, the other is characterized by wheal formation, eosinophilia and other features of an allergic reaction. Gastric irritation, for instance, or acne from iodides or bromides represent intolerance to these drugs
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Enhancement of inflammation by fluorides
Application of ammonium fluoride under an occlusive patch to the abdomen of a rabbit converts a simple scratch into a double row of sterile pustules. Sodium fluoride produces a similar response, but ammonium chloride does not produce pustules. . . . It appears that tissue damage and the presence of fluorides
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Fluoride-Enhanced Inflammation of Skin in Animals:
The possibility that topical fluorides can provoke inflammtory skin disorders gains is supported by carefully controlled studies on animals. When topical fluoride has been applied to the skin of rabbits or rats, inflammation has been repeatedly noted when the skin is cut or damaged prior to the application. Studies Examining Fluoride-Induced Inflammation of Skin in
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Fluoridation, Dialysis & Osteomalacia
In the 1960s and 1970s, doctors discovered that patients receiving kidney dialysis were accumulating very high levels of fluoride in their bones and blood, and that this exposure was associated with severe forms of osteomalacia, a bone-softening disease that leads to weak bones and often excruciating bone pain. Based on
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Skeletal Fluorosis & Individual Variability
One of the common fallacies in the research on skeletal fluorosis is the notion that there is a uniform level of fluoride that is safe for everyone in the population. These "safety thresholds" have been expressed in terms of (a) bone fluoride content, (b) daily dose, (c) water fluoride level, (d) urinary fluoride level, and (e) blood fluoride level. The central fallacy with each of these alleged safety thresholds, however, is that they ignore the wide range of individual susceptibility in how people respond to toxic substances, including fluoride.
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Fluoride & the Immune System - Summation from the US National Research Council (2006)
“There is no question that fluoride can affect the cells involved in providing immune responses. The question is what proportion, if any, of the population consuming drinking water containing fluoride at 4.0 mg/L on a regular basis will have their immune systems compromised? Not a single epidemiologic study has investigated whether fluoride in the drinking water at 4 mg/L is associated with changes in immune function. Nor has any study examined whether a person with an immunodeficiency disease can tolerate fluoride ingestion from drinking water.”
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Prenatal and postnatal ingestion of fluorides - A progress report.
The cases described indicate that certain patients react unfavorably to fluoride therapy. Whether the fluorine acts as an allergen after short term use or whether the fluorine acts as an intoxicant after many months of use, is unknown and should be determined.
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