Excerpt:
Application of ammonium fluoride under an occlusive patch to the abdomen of a rabbit converts a simple scratch into a double row of sterile pustules. Sodium fluoride produces a similar response, but ammonium chloride does not produce pustules. . . .
It appears that tissue damage and the presence of fluorides result in the ‘sterile pustular response.’ This can be called ‘enhancement of inflammation.’ The concentration of fluoride used will not induce inflammation, but it will enhance inflammation. . . .
We are not stating that iodide, fluoride, and nickel necessarily enhance inflammation in identical ways, but there is no doubt that they all enhance the inflammatory response. The fact that each of these substances produces the pustular patch test in man indicates that the reaction is not limited to animals. . . .
Summary
Application of a patch test of fluorides to a scratch on the rabbit’s abdomen converts the lesion to a double row of intraepidermal pustules. There is now experimental data to show that systemic iodide, topical iodide, and topical fluoride produce qualitative changes in the inflammatory cycle. Intraepidermal pustule formation is a new experimental phenomenon. We believe we are exaggerating the first cellular phase of inflammation.
-
-
Prenatal and postnatal ingestion of fluorides: fourteen years of investigation -- final report*.
SUMMARY Data is presented showing that fluoride ingested by gravid women enters the maternal circulation, is stored in the placenta and passes through the placental barrier to enter the foetal blood supply. Evidence is presented that the fluoride in the foetal blood supply affects the developing teeth to make them more resistant
-
Fluoroderma
Papulonodular eruptions from certain bromide and iodide preparations are widely recognized entities, but skin lesions following fluoride ingestion are rare. Modern prophylaxis for postirradiation dental caries includes the use of fluoride gel preparations applied to the teeth. In two patients receiving such therapy a papulonodular eruption developed, similar to the
-
The effect of stannous fluoride and stannous chloride on inflammation
Scratches were made to the depth of the upper dermis on the abdomen of rabbits. The scratches were covered by patch tests for 18 hours with solutions of stannous fluoride or stannous chloride. Both these substances produced a destructive reaction with intraepidermal polymorphonuclear leukocyte pustules occurring on each side of
-
Fluoride tooth paste: a cause of perioral dermatitis
Since its description in 1957 by Frumess and Lewis as a “light-sensitive seborrheid,” perioral dermatitis (PD) has continued to be a perplexing entity. (1) Many causes have been postulated, including sunlight sensitivity, birth control pills, emotional stress, fluorinated steroid creams, Candida albicans, and rosacea. We have gathered clinical and historical data implicating
-
Contact urticaria from sodium fluoride
Sodium fluoride (NaF) is. used for the treatment and prevention of dental caries. Its application to the teeth makes the dental enamel more resistant to acid. In some communities, it is added to the water if the geographical area lacks sufficient fluoride. Another method of preventing dental caries is the
Related Studies :
-
-
-
Fluoride Dentrifice and Stomatitis
Statistical data of 133 patients who have been using fluoride dental cream or powder have been presented. Each has developed intraoral ulcerative lesions. Many have been treated for other complaints without clearance of the lesions. Age is not significant. Repeated insults with the fluoride dentrifices produced increasingly severe excoriations. There seems to be nothing specific about the lesions to differentiate them from other diseases of an oral nature.
-
Factors which increase the risk for skeletal fluorosis
The risk for developing skeletal fluorosis, and the course the disease will take, is not solely dependent on the dose of fluoride ingested. Indeed, people exposed to similar doses of fluoride may experience markedly different effects. While the wide range in individual response to fluoride is not yet fully understood, the following are some of the factors that are believed to play a role.
-
Prenatal and postnatal ingestion of fluorides - A progress report.
The cases described indicate that certain patients react unfavorably to fluoride therapy. Whether the fluorine acts as an allergen after short term use or whether the fluorine acts as an intoxicant after many months of use, is unknown and should be determined.
-
Fluoridation, Dialysis & Osteomalacia
In the 1960s and 1970s, doctors discovered that patients receiving kidney dialysis were accumulating very high levels of fluoride in their bones and blood, and that this exposure was associated with severe forms of osteomalacia, a bone-softening disease that leads to weak bones and often excruciating bone pain. Based on
-
Allergy to Fluorides
Rather than simply denying the validity of his reports, it would be to the advantage of all concerned to have them thoroughly analyzed. This could best be done if a small number of unbiased, qualified physicians, agreed upon by both "sides," would independently examine and diagnose several of the patients who are reportedly allergic to fluoride.
Related FAN Content :
-