Abstract
HF exposure might produce adverse effects in industrial workers. A 3 mo. exposure of rats to HF at 10 mg/m3 8 h/day 5 days/wk resulted in increased blood serum concentrations of hydroxyproline and hydroxylysine and in enhanced urinary excretion of these amino acids and in changes of collagen fractions in the liver, lungs and skin. In all tissues studied (especially liver), soluble and insoluble collagen decreased. HF affected biosynthesis and maturation of collagen fibers.
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Correlations between fluoride concentration and free radical parameters in soft tissues of rats.
In previous studies we investigated the impact of subchronic exposure of rats to sodium fluoride administered in their drinking water as it affected selected biochemical parameters in their soft tissues and organs. The activity of glutathione peroxidase and the concentrations of fluoride, reduced glutathione (GSH), substances reacting with thiobarbituric acid (TBARS), and carbonyl groups were determined in kidney,
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Effects of inhaled HF on lipid metabolism in guinea pigs.
The effects of exposure to inhaled hydrogen-fluoride (7664-39-3) (HF) on lipid metabolism were investigated in male albino-guinea-pigs. One group of animals was exposed to 10 milligrams per cubic meter (m3) HF in a cylindrical plexiglass cage with an air turnover rate of 40m3 per hour for 8 hours. A control
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Investigations of soft tissue functions in fluorotic individuals of North Gujurat
The present study was undertaken to investigate the various health problems caused by water-borne fluoride in endemic villages of Mehsana and Banaskantha districts of Gujarat. The study revealed high levels of fluoride in serum samples of the villagers. Mottling of teeth and skeletal complications were common. Intake of fluoride caused
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Fluoride distribution in rats during and after continuous infusion of Na18F.
Rats were given Na18F as a radiotracer for F- at varying chemical dose rates by continuous i.v. infusion for 3 h. Blood fluoride was assessed 6-7 times over the infusion period, at the end of which the animals were sacrificed for determination of tissue fluoride distribution. At sublethal dosages, the
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Fluoride in Drinking Water: A Scientific Review of EPA’s Standards.
Excerpts: Summary Under the Safe Drinking Water Act, the U.S. Environmental Protection Agency (EPA) is required to establish exposure standards for contaminants in public drinking-water systems that might cause any adverse effects on human health. These standards include the maximum contaminant level goal (MCLG), the maximum contaminant level (MCL), and the secondary
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