Abstract
OBJECTIVES: This study aimed to clarify the relationship between community water fluoridation (CWF) and IQ.
METHODS: We conducted a prospective study of a general population sample of those born in Dunedin, New Zealand, between April 1, 1972, and March 30, 1973 (95.4% retention of cohort after 38 years of prospective follow-up). Residence in a CWF area, use of fluoride dentifrice and intake of 0.5-milligram fluoride tablets were assessed in early life (prior to age 5 years); we assessed IQ repeatedly between ages 7 to 13 years and at age 38 years.
RESULTS: No significant differences in IQ because of fluoride exposure were noted. These findings held after adjusting for potential confounding variables, including sex, socioeconomic status, breastfeeding, and birth weight (as well as educational attainment for adult IQ outcomes).
CONCLUSIONS: These findings do not support the assertion that fluoride in the context of CWF programs is neurotoxic. Associations between very high fluoride exposure and low IQ reported in previous studies may have been affected by confounding, particularly by urban or rural status.
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A Benchmark Dose Analysis for Maternal Pregnancy Urine-Fluoride and IQ in Children.
This article is a preprint and has not been peer-reviewed. It reports new medical research that has yet to be evaluated and so should not be used to guide clinical practice. Abstract As a safe exposure level for fluoride in pregnancy has not been established, we used data from two prospective studies
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Effects of High-Water Fluoride Exposure on IQ Levels in School-Age Children: A Cross-Sectional Study in Jiangsu, China
This cross-sectional research aimed to investigate the potential effects of elevated fluoride levels in drinking water on children’s intelligence quotient (IQ). A total of 721 children from rural Jiangsu, China, were included in the study and divided into two groups based on the fluoride concentration in their drinking water: a
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OP V – 2 Prenatal fluoride exposure and neurobehavior among children 1–3 years of age in Mexico
Background/aim Recent studies report an inverse association between fluoride (F) exposure and IQ in children, but few included individual measures of exposure or assessed associations with prenatal exposure using a prospective study design. Methods This study utilised the Early Life Exposures in Mexico to Environmental Toxicants (ELEMENT) birth cohort and archived pregnancy samples
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Effect of fluoride exposure on Intelligence Quotient (IQ) among 13-15 year old school children of known endemic area of fluorosis, Nalgonda District, Andhra Pradesh.
Background: Waning controversy over fluoride and water fluoridation is rekindling with the findings released from certain fluoride studies which reported an inverse association between fluoride exposure and intelligence. Objective: To assess the relationship between exposure to different drinking water fluoride levels and children's Intelligence Quotient (IQ) among 13-15 year old school
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The influence of fluoride in drinking water on the incidence of fluorosis and intelligence of elementary school students in Palu City.
Abstract Objective This research aims to know the influence of fluoride in drinking water towards Fluorosis and the Intelligence Level of Elementary School Students in Palu City. Method This cross-sectional study was performed through descriptive analysis on 100 students aged 6–12 years old selected by stratified random sampling from two different areas with different
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Fluoride Affects Learning & Memory in Animals
An association between elevated fluoride exposure and reduced intelligence has now been observed in 65 IQ studies. Although a link between fluoride and intelligence might initially seem surprising or random, it is actually consistent with a large body of animal research. This animal research includes the following 45 studies (out
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Fluoride & IQ: 76 Studies
Note: See the Updated list of fluoride IQ studies at https://fluoridealert.org/researchers/fluoride-iq-studies/the-fluoride-iq-studies/ • As of July 18, 2022, a total of 85 human studies have investigated the relationship between fluoride and human intelligence. • Of these investigations, 76 studies have reported that elevated fluoride exposure is associated with reduced IQ in humans. • The studies
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NRC (2006): Fluoride's Neurotoxicity and Neurobehavioral Effects
The NRC's analysis on fluoride and the brain.
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Fluoride's Effect on Fetal Brain
The human placenta does not prevent the passage of fluoride from a pregnant mother's bloodstream to the fetus. As a result, a fetus can be harmed by fluoride ingested pregnancy. Based on research from China, the fetal brain is one of the organs susceptible to fluoride poisoning. As highlighted by the excerpts
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Fluoride: Developmental Neurotoxicity.
Developmental Neurotoxicity There has been a tremendous amount of research done on the association of exposure to fluoride with developmental neurotoxicity. There are 78 studies reporting reduced IQ (75 studies with children and 3 studies with adults) and several on the impaired learning/memory in animals. And there are studies which link
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