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• Exposure to environmental neurotoxic substances and neurodevelopment in children from Latin America and the Caribbean.

  Introduction Environmental neurotoxicants are pollutants that can negatively affect many cellular metabolic-processes through different pathways: neuroendocrine/thyroid hormone disruption (Pb, methyl-Hg, organochlorines, and polychlorinated biphenyls-PCB), oxidative stress (Pb, methyl-Hg, organochlorines, and chlorpyrifos), dopamine dysfunction (Pb, methyl-Hg, As, chlorpyrifos, pyrethroids, and organochlorines) (Heyer and Meredith, 2017; Rock and Patisaul, 2018). Pistollato et al. (2020) studied neurotoxic substances […]

• Inorganic fluoride and functions of brain.

  Note from the Fluoride Action Network: It’s worth noting that this review paper did not include these important Mother-Offspring studies: Bashash-2017, Valdez-Jimenez-2017, Green-2019. Nor did it include the ADHD study by Bashash-2018. Perhaps it was too late for the authors  to have included the Green IQ study published in August 2019, the Riddell -October 2019 […]

• Rachitomimetic effects of fluoride feeding on the skeletal tissues of growing pigs

• Maternal and fetal exposures to fluoride during mid-gestation among pregnant women in northern California.

  Introduction In the United States (US), water and water-based beverages contribute to approximately 75% of the total fluoride intake among adults living in communities that fluoridate their water supply [1]. The most recent estimates posted by the US Centers for Disease Control and Prevention (CDC), are that nearly three-fourths of the U.S. population with access […]

• Sodium fluoride induces apoptosis through the downregulation of hypoxia-inducible factor-1a in primary cultured rat chondrocytes

  Results of previous studies have shown that fluoride has a higher and special affinity for calcium in bone tissue, which could result in osteofluorosis (19,20). It has been reported that osteofluorosis may increase the severity of osteoarthritis (OA) characterized by progressive degeneration of articular cartilage (21,22). Chondrocyte apoptosis may be involved in the onset and […]

• Developmental fluoride neurotoxicity: a systematic review and meta-analysis

• Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses.

• Association between fluoride exposure and kidney function in adults: A cross-sectional study based on endemic fluorosis area in China.

  4. Discussion We examined the relationship between urinary fluoride concentrations and levels of markers of kidney function (urinary NAG, serum RBP, serum Urea, serum C3 serum UA and serum ?1-MG) in a cross-sectional study of endemic fluorosis in China. We found that the levels of urinary NAG and serum Urea increased significantly with the increase […]

• Intelligence and fluoride exposure in New Zealand children

• Fluoride-linked down syndrome births and their estimated occurrence due to water fluoridation