Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Fluoride toothpastes of different concentrations for preventing dental caries.

March 4, 2019 | The Cochrane Database of Systematic Reviews | Walsh T, Worthington HV, Glenny AM, Marinho VC, Jeroncic A. | 3(3):CD007868.
Plain language summary available in English Español ????? Français Hrvatski ??? Bahasa Malaysia Polski ??????? ???? Authors' conclusions Implications for practice Overall, there does appear to be some evidence of a dose-response relationship in the caries-preventive effects of fluoride in toothpastes, with the magnitude of the caries-preventive effect estimate increasing as the distance between the lower and higher fluoride concentrati

Paradigms and Public Health Policy Versus Evidence.

October-December 2007 | Fluoride | Richard G Foulkes, BA, MD.† | 40(4):229–237.
Editor’s Note: The article below is the last scientific paper written by Dr Richard G Foulkes before his death on 3 September 2007. Originally it was submitted to the British Columbia Medical Journal in response to an opinion piece titled “Fear of fluoride—more bark than bite?” published in the September 2006 issue of that journal. In the following month, Dr Foulkes submitted a response to the BCMJ, and on January 4, 2007, James A Wilson, MD, editor of the BCMJ, suggested that Dr Foulkes

Evaluation of fluoride release from commercially available fluoride varnishes.

October 1, 2001 | Journal of the American Dental Association | Castillo JL, Milgrom P, Kharasch E, Izutsu K, Fey M. | 132(10):P1389-1392.
References Murray JJ Winter GB Hurst CP Duraphat fluoride varnish: a 2-year clinical trial in 5-year-old children. Br Dent J. 1977; 143: 11-17 View in Article Scopus (37) PubMed Crossref Google Scholar Holm AK Effect of fluoride varnish (Duraphat) in preschool children. Community Dent Oral Epidemiol. 1979; 7: 241-245 View in Article Scopus (65) PubMed Crossref Google Scholar Petersson LG Arthursson L Ostberg

Protocol for a family-centered behavioral intervention to reduce early childhood caries: the MySmileBuddy program efficacy trial.

May 7, 2021 | BMC Oral Health | Lumsden CL, Edelstein BL, Basch CE, Wolf RL, Koch PA, McKeague I, Leu CS, Andrews H. | 21(1):246.
Background Although largely preventable through diet management and topical fluoride use, early childhood caries (ECC) often progresses to severity that necessitates surgical repair. Yet repair often fails to mitigate caries progression. Needed is an effective behavioral intervention to address underlying behavioral causes. Methods This randomized controlled trial will evaluate the efficacy of a behaviorally focused, family-centered intervention, the MySmileBuddy Program (MSB Program),