Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
-

Use of the Rey-Osterrieth Complex Figure Test for neurotoxicity evaluation of mixtures in children.

November 2009 | Neurotoxicology | Rocha-Amador D, Navarro M, Trejo-Acevedo A, Carrizales L, Pérez-Maldonado I, Díaz-Barriga F, Calderón J. | 30(6):1149-54.
Excerpt 4. Discussion This study provides evidence that children living in high risk areas were exposed to either F, As, Pb, DDT or PCBs and these contaminants could contribute, to some degree, to children’s low performance observed in the tests of the Rey-Osterrieth Complex Figure. The highest proportion of children (89%) with Copy performance below 1 SD was observed in children from F–As area. Approximately 9 out of 10 children were unable to copy the ROCF as expected for their a

Neurotransmitter and receptor changes in the brains of fetuses from areas of endemic fluorosis.

April-June 2008 | Fluoride | Yu Y, Yang W, Dong Z, Wan C, Zhang J, Liu J, Xiao K, Huang Y, Lu B, | 41(2):134–138.
The mothers of the ten fetuses that formed the subject group for this study all had dental fluorosis, with a corresponding increase in urinary fluoride, indicating that these pregnant women were suffering from chronic fluoride poisoning. The excess fluoride of the mother was passed through the placental barrier into the fetus, and from there through the blood-brain barrier to accumulate in the fetal brain, leading to a significant rise in bone and brain fluoride levels. Our results are consiste