Abstract
This study is comprised of 106 male patients over age forty from a high fluoride water (3.5-12.5 ppm) area. These patients have been matched by age and sex with 106 patients from a low fluoride water (0.00-0.45 ppm) area.
All patients had radiograms of the chest, pelvis and both femora; 21 in the fluorotic group underwent a skeletal survey. All plain films were examined for skeletal fluorosis changes; pelvis and femur radiograms for Moenckberg arterial calcifications.
Over age 60, patients in the high-fluoride group showed a significantly higher incidence of Moenckberg calcifications. A highly significant correlation (p < 0.001) was observed between the severity of these calcifications and the severity of skeletal changes within this group.
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Analysis of x-ray heart areas of 30 patients with endemic fluorosis
I. Targets and methods Based on diagnosis standards formulated at the 1981 Shijiazhuang National Prevention of Endemic Fluorosis Meeting, 30 patients were chosen, 15 men and 15 women with an average age of 45, average height of 1.63 meters, and average weight of 54 kilograms, and all with clinical diagnoses
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Fluoride and calcium levels in the aorta
Among soft tissue organs which store fluoride (F-), the aorta contains the highest levels. [1-2]. Calcifications of arteries of the Monckeberg type have been reported in relatively young persons afflicted with skeletal fluorosis from endemic areas. [3-5] It was, therefore, of interest to determine whether or not there is a
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Relationship between fluoride deposition and metastatic calcification in soft tissues of rat and guinea pig
Two studies have been conducted to investigate whether there is a relationship between the disposition of fluoride in various soft tissues of rats and guinea pigs and the levels of calcium and phosphorous in the tissues. The results suggest that when rats receive a stock corn diet there is a
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Aortic calcification in chronic fluoride poisoning: biochemical and electronmicroscopic evidence
Fluoride is known to cause ectopic calcification. The biochemical mechanism(s) involved in the initiation of calcification is not understood and the accompanying ultrastructural changes remain to be elucidated. Therefore, certain relevant parameters have been investigated in the aorta of rabbits administered fluoride, 10 mg NaF/kg body wt, every 24 hr
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Fluorosis in Aden
The cases to be described here occurred in the Aden Protectorate where for the last 12 years mass screening of the chest to exclude pulmonary tuberculosis has been carried out. The patients had all drunk the brackish water from the wells, and the analysis of the water from a well
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