Abstract
This study is comprised of 106 male patients over age forty from a high fluoride water (3.5-12.5 ppm) area. These patients have been matched by age and sex with 106 patients from a low fluoride water (0.00-0.45 ppm) area.
All patients had radiograms of the chest, pelvis and both femora; 21 in the fluorotic group underwent a skeletal survey. All plain films were examined for skeletal fluorosis changes; pelvis and femur radiograms for Moenckberg arterial calcifications.
Over age 60, patients in the high-fluoride group showed a significantly higher incidence of Moenckberg calcifications. A highly significant correlation (p < 0.001) was observed between the severity of these calcifications and the severity of skeletal changes within this group.
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Aortic calcification in chronic fluoride poisoning: biochemical and electronmicroscopic evidence
Fluoride is known to cause ectopic calcification. The biochemical mechanism(s) involved in the initiation of calcification is not understood and the accompanying ultrastructural changes remain to be elucidated. Therefore, certain relevant parameters have been investigated in the aorta of rabbits administered fluoride, 10 mg NaF/kg body wt, every 24 hr
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Effect of water fluoridation on the development of medial vascular calcification in uremic rats
Public water fluoridation is a common policy for improving dental health. Fluoride replaces the hydroxyls of hydroxyapatite, thereby improving the strength of tooth enamel, but this process can also occur in other active calcifications. This paper studies the effects of water fluoridation during the course of vascular calcification in renal
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Histological and chemical studies in man on effects of fluoride
The presence of elevated concentrations of fluorides in the atmosphere has been associated with changes in certain plants and an increase in the fluoride content of forage in certain areas in Utah. Long-term ingestion of such forage by some animals has produced changes characteristic of fluorosis in some of them.
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Analysis of x-ray heart areas of 30 patients with endemic fluorosis
I. Targets and methods Based on diagnosis standards formulated at the 1981 Shijiazhuang National Prevention of Endemic Fluorosis Meeting, 30 patients were chosen, 15 men and 15 women with an average age of 45, average height of 1.63 meters, and average weight of 54 kilograms, and all with clinical diagnoses
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Observations of two-dimensional (2D) echocardiograms in patients with fluorine-associated aortic sclerosis
Forty-six patients with endemic fluorosis were assigned to 4 subgroups based on their age and then received echocardiograms that were compared with echocardiograms of 46 healthy cases in a region affected by fluorosis and 46 healthy cases in a region unaffected by fluorosis via observations; a preliminary exploration was made
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