Abstract

Roentgenograms of the lateral lumbar area of the spine were obtained from 1,015 subjects over age 45 who were residing in North Dakota. Three hundred lived in an area where the fluoride content of the water supply was high, 4 to 5.8 ppm, and 715 in an area where it was low, 0.15 to 0.3 ppm. Evidence of osteoporosis, reduced bone density, and collapsed vertebrae was substantially higher in the low-fluoride area, particularly in men. Limited information on milk and cheese consumption does not indicate that differences in calcium consumption are a significant factor. Fluoride consumption is important in the prevention of osteoporosis and may also play a significant role in preventing calcification of the aorta.

• Related Studies :

  • Fluorosis in Aden

    The cases to be described here occurred in the Aden Protectorate where for the last 12 years mass screening of the chest to exclude pulmonary tuberculosis has been carried out. The patients had all drunk the brackish water from the wells, and the analysis of the water from a well

  • Further observations on radiological changes of endemic food borne skeletal fluorosis

    Among radiological changes in 396 cases of foodborne skeletal fluorosis, from 4 endemic areas in Guizhou, China, osteoporosis, osteomalacia and impaired bone growth were seen in addition to previously recorded findings of osteosclerosis, bone prominences, joint changes and calcification of peripheral arteries. The deformity of genu valgum, a manifestation of

  • Medical aspects of excessive fluoride in a water supply

    A 10-year study of 116 persons in Bartlett and 121 in Cameron, Tex., was conducted to determine if prolonged exposure to fluoride in the water supply of Bartlett had produced detectable physiological effects. Bartlett's water contained about 8 p.p.m. F until 1952, when an experimental defluoridation unit was installed, reducing the

  • Addition of monofluorophosphate to estrogen therapy in postmenopausal osteoporosis: a randomized controlled trial

    INTRODUCTION: Treatment of osteoporosis with high-dose fluoride alone does not reduce fracture risk. We hypothesized that the antifracture efficacy of fluoride could be optimized by its use in low doses combined with an antiresorptive agent. EXPERIMENTAL SUBJECTS: Subjects included 80 women with postmenopausal osteoporosis who had been taking estrogen for at least 1

  • Bone quality in fluoride-exposed populations: A novel application of the ultrasonic method.

    Highlights A novel ultrasonic bone quality biomarker was tested in a population with low to high exposure to F.- Negative associations were found between F- exposure and bone quality Decreased bone quality reflects net bone loss, abnormal mineralization and altered collagen. The finding highlights that F- exposure has complex

• Related FAN Content :

  • Fluoride & Arteriosclerosis

    Healthy arteries are flexible and elastic, allowing efficient transfer of blood and nutrients from the heart to the rest of the body. Arteriosclerosis refers to a stiffening of the arteries, including loss of elasticity. This is a slow, progressive disease that may begin early in life from damage to the

  • Fluoride, Blood Pressure and Hypertension

    Individuals with blood pressure readings that exceed 140/90 are considered hypertensive. Hypertension can increase the risk of stroke, heart attack, heart failure, aortic aneurysms, and peripheral arterial disease. An association between increased fluoride in ground water and increased prevalence of hypertension has been observed, especially among adult males (Amini et

  • Fluoride & Electrocardiogram Abnormalities

    An electrocardiogram (ECG) is a diagnostic test that measures the electrical activity of the heart. An ECG can reveal heart rate, heart rhythym (i.e. steady or irregular), and the strength and timing of the heart’s natural electrical signals. ECGs are described in terms of “waves” (e.g. amplitude and duration). Problems

  • Skeletal Fluorosis: The Misdiagnosis Problem

    It is a virtual certainty that there are individuals in the general population unknowingly suffering from some form of skeletal fluorosis as a result of a doctor's failure to consider fluoride as a cause of their symptoms. Proof that this is the case can be found in the following case reports of skeletal fluorosis written by doctors in the U.S. and other western countries. As can be seen, a consistent feature of these reports is that fluorosis patients--even those with crippling skeletal fluorosis--are misdiagnosed for years by multiple teams of doctors who routinely fail to consider fluoride as a possible cause of their disease.

  • Fluoride & Arterial Calcification

    The major change involved with cardiovascular disease is development of atherosclerosis in critical arteries, which is partially characterized by vascular calcification. The level of coronary artery calcification is thought to be the most important indicator of future cardiovascular events. Increased arterial calcifications have frequently been reported in those with skeletal fluorosis