Fluoride Action Network


Objective: This study was carried out to analyse the electrocardiogram (ECG) in patients with endemic fluorosis. Methods: Fifty six patients with endemic fluorosis and 44 age, sex and body mass index (BMI) matched healthy controls with normal fluoride intake underwent standart 12-lead ECG, urine fluoride level and serum sodium, potassium, calcium and phosphorus determination. Basic ECG measurements and frequency of ECG abnormalities were evaluated. Results: The urine fluoride levels of fluorosis patients were significantly higher than control subjects as expected (1.9 ± 0.2 mg/l vs. 0.4 ± 0.1 mg/l respectively; P<0.001). There were no statistically significant differences between the two groups with respect to age, gender, BMI and serum levels of sodium, potassium, calcium and phosphorus. There were no statistically significant differences between controls and fluorosis patients with respect to heart rate, basic ECG measurements and ECG abnormalities. Results: We concluded that endemic fluorosis has no effect on ECG.