Abstract
Forty-five male patients suffering from chronic fluorine poisoning and fifteen normal men were investigated. The urinary excretion of oestrone, oestradiol-17?, oestriol and 16-epioestriol was studied. The results revealed a high content of oestrogens in urine. This is explained by a metabolic disorder in the liver.
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Collagen metabolism in rats exposed to hydrogen fluoride.
HF exposure might produce adverse effects in industrial workers. A 3 mo. exposure of rats to HF at 10 mg/m3 8 h/day 5 days/wk resulted in increased blood serum concentrations of hydroxyproline and hydroxylysine and in enhanced urinary excretion of these amino acids and in changes of collagen fractions in
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Correlations between fluoride concentration and free radical parameters in soft tissues of rats.
In previous studies we investigated the impact of subchronic exposure of rats to sodium fluoride administered in their drinking water as it affected selected biochemical parameters in their soft tissues and organs. The activity of glutathione peroxidase and the concentrations of fluoride, reduced glutathione (GSH), substances reacting with thiobarbituric acid (TBARS), and carbonyl groups were determined in kidney,
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[An investigation on the effect of Rosa roxburghii tratt juice on chronic fluorosis and its mechanism].
Improved the general condition of chronic fluorosis but had no effect on dental fluorosis enhanced the excretion of fluorine and lowered the fluorine content of serum and bone which has been raised during fluorine intoxication; increased serum vitamin C and protected collagen as manifested by declin[e] of urinary hydroxyproline; inhibited
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Effects of individual and combined exposure to sodium arsenite and sodium fluoride on tissue oxidative stress, arsenic and fluoride levels in male mice.
Arsenic and fluoride are potent toxicants, widely distributed through drinking water and food and often result in adverse health effects. The present study examined the effects of sodium meta-arsenite (100 mg/l in drinking water) and sodium fluoride (5 mg/kg, oral, once daily), administered either alone or in combination for 8
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Fluoride effects on glutathione peroxidase and lipid peroxidation in rats.
SUMMARY: Eight-week old male Wistar rats weighing 180 g were given sodium fluoride in drinking water at a concentration of 5 and 25 mg F–/L for 12 weeks. Control animals received tap water containing 0.3 mg F–/L. The activity of glutathione peroxidase and the concentration of malondialdehye (MDA) were determined
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