Abstract
Objective: To probe into the changing regularity of sclerotic skeletal fluorosis after patients changed to drink low-fluorine water for the long term. Methods: Study subjects were patients with sclerotic skeletal fluorosis who changed to drink low-fluorine water 16–25 years ago, and their sclerotic skeletal fluorosis had been proven by bone X-ray at the beginning of or prior to this change; their anteroposterior X-ray films of the pelvis, right forearm and right lower limb were taken for comparison and analysis. Results: The bone substances of all subjects improved remarkably after they changed to drink low-fluorine water for the long term, and 21.47% of them resumed a normal state. The morphology of bone trabecula was not improved for 18.75%–85.75% of cases, and dense bone trabecula became osteoporotic for most cases. The ossification of peri-osseous soft tissues worsened for 73.33% of cases and the degenerative changes of bone joints worsened for 80%. Conclusion: The bone substances of sclerotic skeletal fluorosis can improve remarkably after patients change to drink low-fluorine water for the long term, and so a portion of patients may resume the normal state. Two consequential effects of sclerotic skeletal fluorosis are osteoporosis and exacerbation of ossification of peri-osseous soft tissues.
-
-
Total hip arthroplasty for the treatment of severe hip osteoarthritis due to fluorosis
BACKGROUND: Now, total hip arthroplasty (THA) is one of the effective methods for the treatment of severe hip osteoarthritis due to fluorosis. OBJECTIVE: To investigate the strategies and efficacy of THA for the treatment of severe hip osteoarthritis due to fluorosis. METHODS: A total of five cases with severe hip osteoarthritis due
-
Health effects of selected chemicals. 3. Cryolite (sodium aluminium fluoride)
Cryolite occurs in the nature as monoclinic crystals or in synthetic form as an amorphous powder. The natural form may be coloured reddish or brown or even black. Cryolite has a melting point >1 000 degrees C and its main use is in the production of aluminum where it forms
-
Early diagnosis and complete recovery from fluorosis through practice of interventions
OBJECTIVES: The objective of this communication is to disseminate scientific and technical information for early diagnosis of Fluorosis; recent developments in care and management of patients of Fluorosis. Material and Methods: Body fluids collected from patients suspected of Fluorosis referred by hospitals, samples of drinking water used by them are the
-
Studies on fluorosis in Mehsana District of North Gujarat.
A survey was conducted in eighteen fluoride endemic villages in Mehsana District of North Gujarat (India). The individuals afflicted with fluorosis were examined for apparent mottled teeth and skeletal complications. Samples of urine and blood of these individuals along with drinking water were collected and compared with samples obtained from
-
Skeletal fluorosis: histomorphometric analysis of bone changes and bone fluoride content in 29 patients
Bone fluoride content (BFC) was measured and histomorphometric analysis of undecalcified sections was performed in transiliac biopsy cores from 29 patients (16 men, 13 women, aged 51 +/- 17 years) suffering from skeletal fluorosis due to chronic exposure to fluoride. The origin of the exposure, known in 20 patients, was either hydric
Related Studies :
-
-
-
Skeletal Fluorosis: The Misdiagnosis Problem
It is a virtual certainty that there are individuals in the general population unknowingly suffering from some form of skeletal fluorosis as a result of a doctor's failure to consider fluoride as a cause of their symptoms. Proof that this is the case can be found in the following case reports of skeletal fluorosis written by doctors in the U.S. and other western countries. As can be seen, a consistent feature of these reports is that fluorosis patients--even those with crippling skeletal fluorosis--are misdiagnosed for years by multiple teams of doctors who routinely fail to consider fluoride as a possible cause of their disease.
-
Fluoride & Osteoarthritis
While the osteoarthritic effects that occurred from fluoride exposure were once considered to be limited to those with skeletal fluorosis, recent research shows that fluoride can cause osteoarthritis in the absence of traditionally defined fluorosis. Conventional methods used for detecting skeletal fluorosis, therefore, will fail to detect the full range of people suffering from fluoride-induced osteoarthritis.
-
"Pre-Skeletal" Fluorosis
As demonstrated by the studies below, skeletal fluorosis may produce adverse symptoms, including arthritic pains, clinical osteoarthritis, gastrointestinal disturbances, and bone fragility, before the classic bone change of fluorosis (i.e., osteosclerosis in the spine and pelvis) is detectable by x-ray. Relying on x-rays, therefore, to diagnosis skeletal fluorosis will invariably fail to protect those individuals who are suffering from the pre-skeletal phase of the disease. Moreover, some individuals with clinical skeletal fluorosis will not develop an increase in bone density, let alone osteosclerosis, of the spine. Thus, relying on unusual increases in spinal bone density will under-detect the rate of skeletal fluoride poisoning in a population.
-
Skeletal Fluorosis Causes Bones to be Brittle & Prone to Fracture
It has been known since as the early as the 1930s that patients with skeletal fluorosis have bone that is more brittle and prone to fracture. More recently, however, researchers have found that fluoride can reduce bone strength before the onset of skeletal fluorosis. Included below are some of the
-
Fluoride Reduces Bone Strength Prior to Onset of Skeletal Fluorosis
The majority of animal studies investigating fluoride's impact on bone strength have found that fluoride has either no effect, or a detrimental effect, on bone strength. Importantly, several of the animal studies that have found fluoride reductes bone strength have reported that this reduction in strength occurs before signs of skeletal fluorosis
Related FAN Content :
-