Abstract
Objective: To determine the fraction of an ingested fluoride dose of 1 mg in 50 mL orange juice that is excreted through the urine (FUEF) of children aged 3-5 years.
Methods: Eighty-eight controlled determinations involving 24-hour urinary collections from a total of 48 children were carried out during consecutive control and test days. Net fluoride urinary excretion due to the ingested dose was calculated as the difference between the total amount of fluoride excreted by each child on test and control days.
Results: Excretion of the fluoride ingested from the single fluoride dose presented an average value of 30.7% (95% CI: 28.9-32.5%). No significant associations were found between individual FUEF values with either anthropometrical variables or urinary pH values. The average FUEF value found in the present study lies between previously reported values for infants and young adults. The epidemiological usefulness of the FUEF values in estimating daily fluoride dose in pre-school children is discussed.
*Original abstract online at https://pubmed.ncbi.nlm.nih.gov/10403091/
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Interaction of fluoride exposure and CREB1 gene polymorphisms on thyroid function in school-age children.
Highlights Serum TT4 level is negatively associated with urinary fluoride concentration. Thyroid volume of children is positively related to urinary fluoride concentration. CREB1 polymorphisms could modify the levels of serum TT3 and TT4. Fluoride exposure and CREB1 SNPs interactions on thyroid volume are observed. Interactions among CREB1 SNPs loci
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Urinary fluoride patterns among children in Mexico and Canada.
Background: New research suggesting fluoride is a developmental neurotoxicant highlights the importance of characterizing fluoride exposure in children. Fluoride is added to salt in Mexico and to drinking water in Canada to prevent dental caries. We examined the association of childhood urinary fluoride (CUF) with food and water fluoride levels
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Urinary minerals excretion among primary schoolchildren in Dubai—United Arab Emirates.
Introduction Urinary excretion of calcium (Ca), magnesium (Mg), phosphorus (P), iodine and fluoride is used to assess their statuses and/or the existence of metabolic abnormalities. In the United Arab Emirates (UAE), the urinary concentration of these minerals among children have not been documented. Materials and methods A cross-sectional study, including 593 subjects (232
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Fluoride exposure during early adolescence and its association with internalizing symptoms.
Highlights Adolescents with elevated urinary fluoride concentrations exhibit more somatization symptoms. Males may represent an at-risk population for fluoride-related internalizing behaviors. While somatization is typically comorbid with anxiety and depression, fluoride concentrations were not associated with increased depressive or anxiety symptoms. Background Early, chronic, low-level fluoride exposure has been linked to
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Association of water fluoride and urinary fluoride concentrations with attention deficit hyperactivity disorder in Canadian youth.
A correction to an error in Table 4 was made. See correction at https://fluoridealert.org/studytracker/41631/ and also below. Highlights UFSG did not significantly predict ADHD diagnosis or ADHD-type symptoms. Higher tap water fluoride was associated with higher odds of an ADHD diagnosis. Higher water fluoride was associated with more ADHD-type symptoms for
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Unheeded Warnings: Government Health Authorities Ignore Fluoride Risk for Kidney Patients
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Mayo Clinic: Fluoridation & Bone Disease in Renal Patients
The available evidence suggests that some patients wtih long-term renal failure are being affected by drinking water with as little as 2 ppm fluoride. The finding of adverse effects in patients drinking water with 2 ppm of fluoride suggests that a few similar cases may be found in patients imbibing 1 ppm, especially if large volumes are consumed, or in heavy tea drinkers. The finding of adverse effects in patients drinking water with 2 ppm of fluoride suggests that a few similar cases may be found in patients imbibing 1 ppm, especially if large volumes are consumed, or in heavy tea drinkers and if fluoride is indeed the cause. It would seem prudent, therefore, to monitor the fluoride intake of patients with renal failure living in high fluoride areas.
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Annapolis: Water Fluoridation Linked to Death of Dialysis Patient
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