Abstract

In order to explore the effects of high fluoride exposure on the reproductive function of male adults, a study was conducted on 31 male adults (20-55 years old) in a high fluoride area with 26 subjects in normal area serving as a control group. The results showed that the levels of serum luteinizing hormone (LH) and follicle-stimulating hormone (FSH) were markedly increased (P<0.001) among the subjects in the high fluoride area; and that the serum level of testosterone (T) was significantly deceased (P<0.01) as compared to the control group. This indicates that high fluoride exposure may affect the reproductive endocrine function of the male human body.

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