Environmental fluoride exposure disrupts the intestinal structure and gut microbiota alteration in duck.

Highlights The gut microbial composition and diversity can be affected by species, diet and external environmental. Fluoride and its compounds can accumulate in animals and plants and threaten human health through the food chain. Fluoride exposure could significantly impair the intestinal barrier and alter the gut microbiota diversity and

Chronic treatment with fluoride affects the jejunum: insights from proteomics and enteric innervation analysis.

Gastrointestinal symptoms are the first signs of fluoride (F) toxicity. In the present study, the jejunum of rats chronically exposed to F was evaluated by proteomics, as well as by morphological analysis. Wistar rats received water containing 0, 10 or 50 mgF/L during 30 days. HuC/D, neuronal Nitric Oxide (nNOS),

Alteration in gastric secretion of rats administered NaF

The effects of sodium-fluoride (7681494) on gastric secretion were studied in rats. Male albino-rats were administered 25 milligrams per kilogram sodium-fluoride in their drinking water for 60 days. Selected rats were killed after 7, 15, 30, and 60 days, and stomachs were dissected out, the gastric juice collected, and the

Fluorine Intoxication: A Clinical-Hygienic Study with a Review of the Literature and Some Experimental Investigations

Prenatal and postnatal ingestion of fluoride salts: a progress report.

Undesirable Effects Out of the 601 cases in the adult group, six have shown undesirable side effects from the fluoride supplement. Five out of the 495 children have presented evidence of undesirable reactions. This is 1 per cent incidence of side effects. Reactions in Adults - Included in the adult cases are

Fluoride & Gastrointestinal System: The Importance of Fluoride Concentration in Stomach

The following is an excerpt from the National Research Council's (2006) review of fluoride toxicity: "It is important to realize that GI effects depend more on the net concentration of the aqueous solution of fluoride in the stomach than on the total fluoride dose in the fluid or solid ingested. The

Gastrointestinal Problems Among Individuals with Skeletal Fluorosis

Humans suffering from skeletal fluorosis are known to suffer from an increased occurrence of gastrointestinal disorders. When fluoride intake is reduced, these gastrointestinal problems are among the first symptoms to disappear. The following are some of the studies that have examined this issue: "It is clear from the observations presented in this article

Fluoride-Induced Gastric Symptoms in Human Clinical Trials

In studies where fluoride has been used (at doses of 18-34 mg/day) as an experimental drug for the treatment of osteoporosis, gastrointestinal disturbances are one of the two main side effects consistently encountered. The following are some of the accounts from the published literature: "The use of fluoride in the prophylaxis or

Side Effects from Fluoride Gels: Gastric Distress

Gastric distress -- including nausea, pain, and vomiting -- is one the most common side effects from professional application of "fluoride gels" at the dentist. Patients receiving fluoride gels can swallow more than 20 mg of fluoride from a single treatment -- doses that far exceed the doses that can

Fluoride-Induced Damage to Gastric Mucosa in Human Clinical Trials

When fluoride has been used (at doses of 18-34 mg/day) as an experimental treatment for osteoporosis, gastric pain is one of the two main side effects consistently encountered. To better understand how fluoride causes this effect, researchers have sought to determine how fluoride affects the tissue that lines the gastrointestinal tract. In a