Abstract
PURPOSE: The aim of the study was to determine salivary fluoride concentrations after tooth-brushing with fluoride toothpastes with and without rinsing of oral cavity.
MATERIAL AND METHODS: Fluoride levels in the supernatant of unstimulated mixed saliva were measured after tooth-brushing with Elmex (amine fluoride, 0.125% F) and Meridol (amine fluoride, stannous(II) fluoride, 0.14% F) toothpaste with and without rinsing. Fluoride concentration was measured using a fluoride ion-specific electrode (Orion 96 09BN) connected to a CPI-551 computer. The study was done in 120 subjects from whom salivary samples were taken before and after 15 and 30 min. from tooth-brushing with and without rinsing.
RESULTS: Fluoride levels in saliva correlated with time from tooth-brushing and with oral cavity rinsing. Toothbrushing with rinsing led to similar increase/decrease in fluoride level in saliva for both toothpastes. The use of toothpaste without rinsing vs rinsing produced a two-fold increase in the level of salivary fluoride in the case of Elmex and a three-fold increase in the case of Meridol toothpaste. Fluoride content in saliva 30 minutes after brushing was higher than baseline.
CONCLUSION: Significantly higher fluoride levels in saliva after tooth-brushing with fluoride toothpastes were noted when tooth-brushing was not followed by oral cavity rinsing.
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Fluoride Levels in Saliva and Plaque following the Use of High Fluoride and Conventional Dentifrices- a Triple Blinded Randomised Parallel Group Trial.
Context: The comparison of fluoride levels in saliva and plaque following the use of conventional, 2800 and 5000 ppm dentifrices for different time intervals up to 24 hours has not been explored. Aim: The aim of the present study was to assess salivary and plaque fluoride levels at different time intervals
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A randomised oral fluoride retention study comparing intra-oral kinetics of fluoride-containing dentifrices before and after dietary acid exposure.
Highlights Fluoride can protect enamel from demineralisation and promote remineralization. A sodium fluoride/potassium nitrate/cocamidopropyl betaine dentifrice was examined. Compared to a NaF/KNO3/sodium lauryl sulphate/tetrasodium pyrophosphate dentifrice. Greater salivary fluoride/calcium ion concentration found with the test dentifrice. Formulation excipients may impact fluoride and calcium ion oral cavity retention. OBJECTIVE: This exploratory,
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Randomised study of intra-oral kinetics of fluoride-containing toothpastes.
Objectives: This randomised, controlled, analyst blind, crossover study aimed to evaluate and compare salivary fluoride and calcium ion concentration over 60 min following brushing with an assigned treatment and following an orange juice (OJ) or deionised (DI) water rinse 60 min post-brushing. Methods: Study treatments, both containing
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Salivary fluoride concentration following toothbrushing with and without rinsing: a randomised controlled trial.
Background: Caries prevalence has declined significantly since the introduction of fluoridated toothpaste. There have been several developments regarding specific active fluoride ingredients but not enough evidence to support one over the other. The purpose of this double-blind randomized controlled trial was to compare salivary fluoride concentrations of different
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Assessing Fluorosis Incidence in Areas with Low Fluoride Content in the Drinking Water, Fluorotic Enamel Architecture, and Composition Alterations.
There is currently no consensus among researchers on the optimal level of fluoride for human growth and health. As drinking water is not the sole source of fluoride for humans, and fluoride can be found in many food sources, this work aimed to determine the incidence and severity of dental
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Fluoride & Perioral Dermatitis
Perioral dermatitis (PD) is a common rosacea-like dermatitis that was never reported prior to the mid-fifties. Although it can affect both sexes and all ages, most patients are women ages 20-50 years. Patients with PD frequently report a pre-existing tendency to blush. This disease is most likely multifactorial in origin, and fluoride preparations in dentrifices probably have played a role as precipitator.
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Acute Fluoride Toxicity from Toothpaste Ingestion
The Food & Drug Administration now requires that all fluoride toothpastes sold in the United States bear the following poison warning: "WARNING: Keep out of reach of children under 6 years of age. If you accidentally swallow more than used for brushing, seek professional help or contact a poison control center immediately." The
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Fluoride Toothpaste: A Cause of Perioral Dermatitis
We have gathered clinical and historical data implicating fluoride dentrifices as an important etiologic factor in this dermatosis. The following two cases support this observation.
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Fluoride Dentrifice and Stomatitis
Statistical data of 133 patients who have been using fluoride dental cream or powder have been presented. Each has developed intraoral ulcerative lesions. Many have been treated for other complaints without clearance of the lesions. Age is not significant. Repeated insults with the fluoride dentrifices produced increasingly severe excoriations. There seems to be nothing specific about the lesions to differentiate them from other diseases of an oral nature.
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Allergy to Fluoride
Six children and one adult exhibited various allergic reactions after the use of toothpaste and vitaimin preparations containing fluoride. The following conditions were encountered: Urticaria, exfoliative dermatitis, atopic dermatitis, stomatitis, gastro-intestinal and respiratory allergy.
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