Abstract
A number of cases of goiter have been reported from Ban Mae Toen (BMT) northwestern Thailand, therefore we carried out this study to evaluate the prevalence and severity of goiter in BMT. We suspected fluoride toxicity as a factor in this phenomenon, therefore we used a WHO model using photographs to carry out a non-medical survey for teeth discoloration and limb deformity at the same time as the goiter survey. Every resident of BMT and a sampled population from two nearby control villages were surveyed in 2007. The overall prevalence of goiter among both sexes was 11%; 20% in women and 3% in men. No cases of goiter were recognised in the two control villages. Twenty-four percent of the BMT population and 5% of the sampled population of the control villages had lower limb deformities. Sixty-three percent of the BMT population had discoloration of teeth, especially among those > 35 years old. The control villages had significantly (p < 0.01) fewer cases of discoloration of teeth than the BMT population. The morbidity seen in Ban Mae Toen suggests the need for urgent enquiry into the etiology of this morbidity.
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Functional state of thyroid under extended exposure to fluorides
The issue of specific effect of fluorine on the thyroid in humans remains debatable. There is no doubt, however, that cases of experimental fluorosis are characterized by specific toxicity of fluorine to the thyroid. The hypoactivity of thyroid epithelium is observed, the destructive changes in the follicular cells increasing with the
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[Effect of different fluoride and iodine concentration in drinking water on children's dental fluorosis and thyroid function].
Objective: To investigate the effect of different concentrations of fluoride and iodine in drinking water on children's dental fluorosis and thyroid function. Methods: According to different concentration of fluoride and iodine in drinking water, four villages in two counties of Henan province were classified as high fluoride and iodine, high fluoride,
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Studies of the effect of salt iodization on endemic goiter in Taiwan. IV. A survey of drinking-water in relation to endemic goiter.
No abstract available
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The investigation of effects of fluorosis on thyroid volume in school-age children
Aim To compare the urine iodine, luoride, and to measure thyroid volumes in 10-15-year-old children using ultrasonography, a gold standard in evaluating thyroid volume. Methods A total of 261 children were enrolled into the study group from the 4-8th grades of 3 different primary schools, which were in the zone with high fluoride
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[Effects of fluoride on thyroid structure in chicks].
Objective: To investigate the effects of fluoride on thyroid structure in chicks. Methods: 250 one day chicks were randomly divided into 5 groups, 50 for each. Group I was the control, and other four groups, group II, III, IV, V were fed the diets containing 500, 1,000, 1,500, 2,000 mg/kg of
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Fluorine in the Aetiology of Endemic Goitre
The distribution of endemic goitre in the Punjab and in England is related to the geological distribution of fluorine and to the distribution of human dental fluorosis (mottled enamel). Inquiry showed the presence of dental fluorosis among school-children in two areas of Somerset where two previous observers had recorded a high incidence of goitre, and the absence of dental fluorosis in an adjoining area selected as control where endemic goitre was absent.
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Fluoride, Water Hardness, and Endemic Goitre
Variations in goitre prevalence were found to correlate closely with the fluoride content (p=0-74; P<0-01) and with the hardness (p=0.77; P<0-01) of the water in each village. The effects of fluoride and water hardness seem to be independent.
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Fluoride & Goiter
Goitre (aka goiter) is an enlargement of the thyroid gland that in some cases can produce visible swelling in the neck. The main cause of goitre is iodine deficiency. Goitre can also be caused by other things, including hypothyroidism and substances that cause goitre (goitrogens). Since as far back as the
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The Relationship Between Fluoride Exposure & Goitre in South Africa
As a general rule simple goitre, irrespective of the cause, can be very, or fairly, satisfactorily combated by an adequate increase in man's daily iodine intake, except when the enlargement of the gland is due to the ingestion of excessive amounts of fluorine. The only correct solution to fluorine-induced endemic goitre is the removal of this element from the drinking water.
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Fluoride Aggravates Thyroid Damage Caused by Excess Iodine Intake
Chinese researchers have found that the combination of excess fluoride with excess iodine caused greater reductions in IQ, or greater increases in goitre than either scenario by itself.
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