Tag: Autophagy
Showing 10 of 30:
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Fluoride induces apoptosis and autophagy through the IL-17 signaling pathway in mice hepatocytes.
Excerpts: Apoptosis, characterized by nuclear fragmentation, chromatic condensation, and caspase activation, is a major molecular mechanism to eliminate cells (Oropesa-.vila et al. 2017 ). Apoptosis is observed widely in liver diseases (Cui et al. 2018 ; Potz et al. 2016 ). Fluoride, as an exogenous toxicant, has been reported to cause apoptosis in the liver […]
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Sodium fluoride induces splenocyte autophagy via the mammalian targets of rapamycin (mTOR) signaling pathway in growing mice.
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Chronic treatment with fluoride affects the jejunum: insights from proteomics and enteric innervation analysis.
EXCERPTS … Generally, many studies report Rab proteins as molecules present in the CNS and their specific roles. Although marked differences distinguish the neuronal function between the ENS [Enteric Nervous System] and CNS, their similarities allow the use of some principles established for the brain environment to be reapplied in the enteric context 38. Several […]
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TGF-ß1 acts as mediator in fluoride-induced autophagy in the mouse osteoblast cells.
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Fluoride-Induced Autophagy via the Regulation of Phosphorylation of Mammalian Targets of Rapamycin in Mice Leydig Cells.
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Excessive ER stress and the resulting autophagic flux dysfunction contribute to fluoride-induced neurotoxicity.
from 4. Discussion … In order to gain a better understanding of the NaF neurotoxicity and its underlying mechanisms, the NaF-treated rats and SH-SY5Y cells were used in the present study. The MWM [Morris water maze test] results showed that exposure of rats to NaF is associated with decreased learning and memory abilities. This is […]
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[In vivo and in vitro experimental study on the effect of fluoride-induced autophagy in rat HAT-7 cell line].
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Excessive apoptosis and defective autophagy contribute to developmental testicular toxicity induced by fluoride
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ER-stress caused by accumulated intracistanal granules activates autophagy through a different signal pathway from unfolded protein response in exocrine pancreas cells of rats exposed to fluoride.
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Sirtuin1 and autophagy protect cells from fluoride-induced cell stress