Saturday, November 20th, 2021

Progress of Signaling Pathways, Stress Pathways and Epigenetics in the Pathogenesis of Skeletal Fluorosis.

1. Introduction Fluorine is one of the most common halogens, which usually exists in the environment as compounds. Fluorine or fluoride enters the human body primarily through drinking water, food, and air. Once absorbed into the bloodstream, it is easily transported throughout the body in the form of ions. More than 90% of absorbed fluoride […]

Sunday, August 25th, 2019

Influence of calcium supplementation against fluoride-mediated osteoblasts impairment in vitro: Involvement of canonical Wnt/B-catenin signaling pathway.

Friday, March 29th, 2019

[Biological exposure limits caused by co exposure to fluoride and arsenic based on Wnt signaling pathway].

Sunday, August 12th, 2018

Fluoride Induces Neuroinflammation and Alters Wnt Signaling Pathway in BV2 Microglial Cells.

Fluoride exposure increases IL-1B and TNF-a production and changes the cellular oxidation and antioxidation status [5, 19]. Neuroinflammation seems to be an important mediator of the effects of fluoride. Neuroinflammation, which is mediated by microglia, contributes to most pathological neurologic processes, including CNS infections, ischemic stroke, neurodegenerative disease, and anesthetic neurotoxicity. Increased pro-inflammatory mediator production […]

Sunday, March 9th, 2014

Fluoride promotes osteoblastic differentiation through canonical Wnt/B-catenin signaling pathway

Sunday, February 16th, 2014

Suppression of Sclerostin and Dickkopf-1 levels in patients with fluorine bone injury