Abstract
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Association of Down's syndrome and water fluoride level: a systematic review of the evidence
Background: A review of the safety and efficacy of drinking water fluoridation was commissioned by the UK Department of Health to investigate whether the evidence supported a beneficial effect of water fluoridation and whether there was any evidence of adverse effects. Down's syndrome was one of the adverse effects reported. The
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Editorial review: Fluoride and down's syndrome (mongolism)
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Fluoride-linked down syndrome births and their estimated occurrence due to water fluoridation
Down syndrome (DS) birth rates (BR) as a function of maternal age exhibit a relatively flat linear regression line for younger mothers and a fairly steep one for older mothers with the second line intersecting the first line a little above maternal age 30. Consequently, overall DS-BR for all maternal
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Role des inhibiteurs enzymatiques dans l'etiologie du mongolisme
1) The low incidence of dental caries observed in mongoloid patients led to an investigation of the role of fluorine in this condition. 2) A statistical study of the geographical distribution of mongolism in Wisconsin, Illinois, Idaho, North and South Dakota (U.S.A.) shows a parallelism between the prevalence of this condition
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Water fluoridation and congenital malformations: no association
Data based on a total number of 1,387,027 births were used to compare the incidence of selected congenital malformations in fluoridated areas and that in areas where the water supply is deficient in fluoride. The incidence of selected congenital malformations in areas with fluoride supplementation of public water supplies was compared
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