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Role des inhibiteurs enzymatiques dans l'etiologie du mongolisme
1) The low incidence of dental caries observed in mongoloid patients led to an investigation of the role of fluorine in this condition. 2) A statistical study of the geographical distribution of mongolism in Wisconsin, Illinois, Idaho, North and South Dakota (U.S.A.) shows a parallelism between the prevalence of this condition
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[New researches on mongolism related to the disease producing role of fluorine].
A new statistical study on the distribution of mongolism in cities in Illinois, United States, from January 1, 1950 to December 31, 1956, permits us to verify an increasing frequency of this affliction associated with the concentration of fluorine in the drinking water. This study follows a preceding inquiry on the
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Oligophrenie mongolienee et caries dentaires
Une enquête épidémiologique sur la fréquence du mongolisme dans quelques Etats du Midwest américain nous a permis de mettre en évidence les faits suivants: 1: un parallélisme entre la fréquence du mongolisme et la teneur en fluor de l'eau de boisson; 2: une rareté relative des caries dentaires chez les mongoliens; 3: une
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Sodium fluoride as potential mutagen in mammalian eggs
Evidence from other forms demonstrating mitotic chromosome damage has suggested that sodium fluoride (NaF), a primary air pollutant, be explored as a mutagenic compound in female mammalian germ cells. In vitro experiments with mouse, sheep, and cow oocytes have disclosed a low incidence of anaphase lags, suppression of polar body
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Fluoridation and the occurrence of Down's syndrome
The prevalence rates of Down's syndrome at birth were compared for Massachusetts residents ingesting fluoridated and non-fluoridated water. The observations included nearly all children born alive with Down's syndrome in Massachusetts during the 17-year period 1950-1966. A rate of 1.5 cases per 1000 births was found for fluoride-related births and
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Editorial review: Fluoride and down’s syndrome (mongolism)
Burgstahler AW.
Journal Name: Fluoride
Publish Date: January 1975
Volume/Page: 8(1):1-11.
Type: Review
Categories: Fetal Toxicity & Teratology, Downs Syndrome, Genotoxicity