Abstract
The effect of sodium fluoride on Rana temporaria tadpoles was investigated by adding it in the doses of 1, 2 and 10 mg/lilre to the aquaria where the tadpoles were kept. In all three groups the time of metamorphosis was delayed as compared with that of the controls. Histological examination of the thyroid glands revealed that in the three experimental groups the thyroids were less active than those of the controls.
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The synergistic action of thyroid on fluoride toxicity
Control rats on the basic diets employed developed normal or nearly normal incisor teeth. Rats on the same basic diets to which dried thyroid had been added developed incisor teeth that were markedly bleached due to a potentiation of the toxic action of the fluorine in the basic diet. Subcutaneous
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Effects of fluoride on metamorphosis, thyroid and skeletal development in Bufo gargarizans tadpoles
This study examined the effects of chronic fluoride exposure on metamorphosis, thyroid and skeletal development in tadpoles of Chinese Toad, Bufo gargarizans. The tadpoles were exposed to fluoride concentrations either at 0, 1, 5, 10, or at 50 mg L(-1) from Gosner stage 26 to Gosner stage 42. Body weight,
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Study of excess fluoride ingestion and thyroid hormone derangement in relation with different fluoride levels in drinking water among children of Jodhpur District, Rajasthan, India.
The study was carried out in selected villages of Jodhpur district of Rajasthan. Study area was divided into four categories with different fluoride levels in drinking water. Total 100 children aged 8-14 years were screened for dental fluorosis and biochemical analysis. 25 children were selected from each category. The dental
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Fluorosis and iodine deficiency disorders in India.
This review focuses on fluorosis and iodine deficiency disorders, two serious, highly prevalent metabolic disorders that are under-reported. These are caused by the two elements of the halogen family, fluorine and iodine. The former in excess and the latter in deficiency are the cause for concern. Excess fluoride (F–) consumption
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[The interrelationship of the thyroid and immune statuses of workers with long-term fluorine exposure].
Thyroid and immune statuses were studied in workers continuously exposed to fluorine. The examinees with euthyroid condition had immune disorders with an allergic tendency (increased number of B-lymphocytes, immunoglobulins A). In workers with subclinical hypothyrosis (tri-iodothyronine reduced in 51%), the immune alterations were more evident, T-lymphocytes count rose, but their
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NRC (2006): Fluoride's Impact on the Thyroid Gland
Several lines of information indicate an effect of fluoride exposure on thyroid function. It is difficult to predict exactly what effects on thyroid function are likely at what concentration of fluoride exposure and under what circumstances.
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The Relationship Between Fluoride Exposure & Goitre in South Africa
As a general rule simple goitre, irrespective of the cause, can be very, or fairly, satisfactorily combated by an adequate increase in man's daily iodine intake, except when the enlargement of the gland is due to the ingestion of excessive amounts of fluorine. The only correct solution to fluorine-induced endemic goitre is the removal of this element from the drinking water.
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Fluoride Aggravates Thyroid Damage Caused by Excess Iodine Intake
Chinese researchers have found that the combination of excess fluoride with excess iodine caused greater reductions in IQ, or greater increases in goitre than either scenario by itself.
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Fluoride's Impact on Thyroid Hormones
Up through the 1950s, doctors in Europe and South America prescribed fluoride for this purpose in patients with hyperthyroidism. (Merck Index 1968). Fluoride was selected as a thyroid suppressant based on findings dating back to the mid-19th century that fluoride is a goitrogen (a substance that can cause goiter). When used as
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Is fluoride-induced hyperthyroidism a cause of psychosis among East African immigrants to Scandinavia?
When people with a compensated fluoride-induced hypothyroidism move to a low-fluoride area, the fluoride-induced inhibition of the production of thyroid hormones ceases. In Scandinavia, the dietary intake of iodine is usually quite high due to iodized table salt and easy access to marine fish. Under these conditions, the elevated capacity for production of thyroid hormones may result in hyperthyroidism.
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