To investigate the effect of coal-burning endemic fluorosis on children’s physical development and intellectual level so as to provide data support for the protection of children’s healthy growth in fluorosis areas.
Ninety children with coal-burning endemic fluorosis were selected for the study, which were divided into heavy fluorosis area group, middle fluorosis area group and light disease area group. 30 children in each group. Another 30 children were selected from non-fluorosis areas as normal group. The index of physical development and intellectual level of each group were compared.
Dental fluorosis and urinary fluoride concentration of fluorosis area groups were higher than that of normal group (P<0.05); index of height, weight and vital capacity in normal group children’s was significantly better than that of other 3 groups (P<0.050); intelligence quotient (IQ) index in fluorosis groups was lower than that of normal group (P<0.05).
The coal-burning endemic fluorosis may have a serious impact on children’s physical growth and intellectual level, active preventive measures should be attached to protect children’s health.
Investigation on children’s growth and development under long-term fluoride exposure
Objective To study the influence on children’s growth by long-term high fluoride exposure. Methods Case group was selected in high fluoride areas and control group was selected in non-high fluoride areas. The difference of children’s growth levels were analyzed between 2 groups. Results The IQ of case group was significantly lower than that of control
Fluoride exposure, dopamine relative gene polymorphism and intelligence: A cross-sectional study in China.
Highlights Urine fluoride was inversely associated with IQ. IQ of children with high-activity MAOA genotype was lower than IQ of those with low-activity or female heterozygote genotype. DAT1 and MAOA gene polymorphism modify the effects of UF on IQ. UF, ANKK1, COMT and MAOA have a high-dimensional interaction on
Arsenic and fluoride exposure in drinking water: children’s IQ and growth in Shanyin County, Shanxi Province, China.
Background: Recently, in a cross-sectional study of 201 children in Araihazar, Bangladesh, exposure to arsenic (As) in drinking water has been shown to lower the scores on tests that measure children’s intellectual function before and after adjustment for sociodemographic features. Objectives: We investigated the effects of As and fluoride exposure on
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Cretinism in iodine-deficiency areas is well known, yet the milder forms of somatic and psychomotor maldevelopment and thyroid dysfunction caused by iodine deficiency may be more difficult to detect. DeQuervain, in 1936, called this milder form "semi-cretinism," while in 1980 Laggasse used the term "cretinoidism." It was formally named "subclinical
Blood lead of children in Wamiao-Xinhuai intelligence study (Letter).
As an additional part of our investigation of an association between fluoride in drinking water and children’s intelligence in two villages of Sihong County, Jiangsu Province, China, we have now determined blood lead levels of children in that study. Blood samples (80 ?L) were collected on June 18 and 19, 2003
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