Abstract
Objective
To investigate the effect of coal-burning endemic fluorosis on children’s physical development and intellectual level so as to provide data support for the protection of children’s healthy growth in fluorosis areas.
Methods
Ninety children with coal-burning endemic fluorosis were selected for the study, which were divided into heavy fluorosis area group, middle fluorosis area group and light disease area group. 30 children in each group. Another 30 children were selected from non-fluorosis areas as normal group. The index of physical development and intellectual level of each group were compared.
Results
Dental fluorosis and urinary fluoride concentration of fluorosis area groups were higher than that of normal group (P<0.05); index of height, weight and vital capacity in normal group children’s was significantly better than that of other 3 groups (P<0.050); intelligence quotient (IQ) index in fluorosis groups was lower than that of normal group (P<0.05).
Conclusion
The coal-burning endemic fluorosis may have a serious impact on children’s physical growth and intellectual level, active preventive measures should be attached to protect children’s health.
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Fluoride exposure, dopamine relative gene polymorphism and intelligence: A cross-sectional study in China.
Highlights Urine fluoride was inversely associated with IQ. IQ of children with high-activity MAOA genotype was lower than IQ of those with low-activity or female heterozygote genotype. DAT1 and MAOA gene polymorphism modify the effects of UF on IQ. UF, ANKK1, COMT and MAOA have a high-dimensional interaction on
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Investigation on children’s growth and development under long-term fluoride exposure
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Research on the effects of fluoride on child intellectual development under different environmental conditions.
Goal: To study the effects of the fluoride and iodine content of drinking water on child intellectual development and the interaction between the two factors and also the relationship of educational factors to such development. Methods: The subjects of the investigation were 8- to 14-year-old children randomly selected from endemic areas as well
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Blood lead of children in Wamiao-Xinhuai intelligence study (Letter).
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