Abstract
Using the Wechsler Preschool and Primary Scale of Intelligence, we conducted a study to determine the intellectual ability of 147 four- to seven-year-old preschool children in a high fluoride zone [of a rural area of Shehezi in Xinjiang Province, China] and 83 similarly-aged children from a low fluoride zone in the same region. The results show that a high fluoride intake has a clear influence on the IQ of preschool children, manifesting itself primarily as damage to performance intelligence. The study also indicates that the proportion of preschool children living in the high fluoride area that have retarded head development (based on measurement of the circumference) is significantly greater than in the low fluoride control group, and that children with this developmental deficiency demonstrate a lower IQ than children with normal head development.
Translated by Julian Brooke for Fluoride Action Network and published with the permission of the Endemic Diseases Bulletin (China) 1996;11(1):60-2 and published in the journal Fluoride.
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Developmental Fluoride Neurotoxicity: Choi et al. Respond
Sabour and Ghorbani’s comments about the reported mean difference in IQ (intelligence quotient) scores reported in our article (Choi et al. 2012) suggest a misunderstanding of the scale unit we used and the public health significance of even a small decrease in the average IQ associated with exposure. We appreciate
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Developmental fluoride neurotoxicity: a systematic review and meta-analysis
BACKGROUND: Although fluoride may cause neurotoxicity in animal models and acute fluoride poisoning causes neurotoxicity in adults, very little is known of its effects on children's neurodevelopment. OBJECTIVE: We performed a systematic review and meta-analysis of published studies to investigate the effects of increased fluoride exposure and delayed neurobehavioral development. METHODS: We
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Studies of relationships between the polymorphism of COMT gene and plasma proteomic profiling and children’s intelligence in high fluoride areas
Part I – Effect of high F drinking water on children’s IQ Objective: To investigate the relationships among the children’s serum F, urine F, thyroid hormone levels and children’s IQ in the high fluoride areas. Methods: We collected the samples of the drinking water, urine and blood and measured the F concentrations,
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The effects of endemic fluoride poisoning caused by coal burning on the physical development and intelligence of children.
Goal: To investigate the effects of endemic fluoride poisoning caused by coal burning on the physical development and intellectual ability of children. Method: Using random sampling from the relevant population, 176 fluorosis sufferers aged 7–12 (the subjects) were drawn from a heavily fluoride poisoned area of Zhijin County, with 50 children without dental
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Effects of high iodine and high fluorine on children’s intelligence and thyroid function.
Objective: Try to find out the effects of high iodine and high fluorine on children’s intelligence and thyroid function. Methods: We selected in Qingyun County the Lidian Primary School, where the iodine and fluorine in the water are relatively high in concentration as the investigative point and Dading Primary School where the iodine and
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