Abstract

We used the Orion fluoride electrode system to determine the normal range of serum ionic fluoride concentrations and to investigate its relationship to sex and age (A). 87 normal men, aged 18-92 years (mean, 46 years), and 49 normal women, age 19-64 years (mean, 38 years), participated in the study. At the 95% confidence limits, males less than 45 years old had a normal range of 0.29 to 1.52 mumol/litre and males greater than or equal to 45 years old 0.29 + 0.0101 (A-45) to 1.52 + 0.0101 (A-45) mumol/litre. Females, however, had a normal range of 0.022A – 0.32 to 0.022A + 1.07 mumol/litre. A group of 51 men 18-44 years old was compared with a group of 36 men 46-92 years old. The mean serum F- of the older group was shown to be significantly greater (P less than 0.01) than that of the younger group. Factors related to serum ionic fluoride values are (a) tea as an important source of dietary F-, (b) the lack of significant variation during daytime hours, and (c) the lack of significant difference in concentration between serum and plsma F-.

• Related Studies :

  • Fluoride concentrations in the human placenta and maternal and cord blood

    Fluoride concentrations in maternal and cord blood were measured for the first time with a method specific for inorganic fluoride. The concentrations averaged 0.88 ?M in blood from 16 mothers and 0.68 ?M in the cord blood, with a correlation of 0.86. These results are consistent with the hypothesis that

  • Association between fluoride exposure and cardiometabolic risk in peripubertal Mexican children.

    Highlights Fluoride has been added to table salt in Mexico to reduce dental caries. Human studies of fluoride exposure and metabolic syndrome are rare. We examined the association between fluoride and cardiometabolic risk factors. Fluoride may increase the risk of cardiometabolic disorders in Mexican girls. BACKGROUND: Several animal studies have suggested

  • Transplacental passage of fluoride in pregnant Polish women assessed on the basis of fluoride concentraions in maternal and cord blood plasma.

    The aim of this study was to evaluate placental transfer of fluoride (F) in 30 pregnant women at the time of giving birth, who were living in Poznan, Poland, where the F concentration in the drinking water ranges from 0.4 to 0.8 mg/L. F concentrations of maternal and umbilical venous

  • Serum and urine fluoride concentration: relationships to age, sex and renal function in a non-fluoridated population

    Serum and urine fluoride levels were determined in 250 healthy subjects (15-90 years, 122 men and 128 women) residing in Catalonia, Spain, and in 150 patients (20-81 years, 84 men and 66 women) with chronic renal failure undergoing regular dialysis treatment, living in the same geographical area, to determine normal

  • Fluoride exposure and sleep patterns among older adolescents in the United States: a cross-sectional study of NHANES 2015–2016.

    Abstract Background Fluoride from environmental sources accumulates preferentially in the pineal gland which produces melatonin, the hormone that regulates the sleep-wake cycle. However, the effects of fluoride on sleep regulation remain unknown. This population-based study examined whether chronic low-level fluoride exposure is associated with sleep patterns and daytime sleepiness among older adolescents

• Related FAN Content :

  • Fluoride Exposure Aggravates the Impact of Iodine Deficiency

    A consistent body of animal and human research shows that fluoride exposure worsens the impact of an iodine deficiency. Iodine is the basic building block of the T3 and T4 hormones and thus an adequate iodine intake is essential for the proper functioning of the thyroid gland. When iodine intake is inadequate during infancy and

  • Annapolis: Water Fluoridation Linked to Death of Dialysis Patient

    EVENING CAPITAL (Annapolis, Maryland) November 29, 1979 Fluoride Linked to Death by Mary Ann Kryzankowicz Staff Writer Fluoride poisoning has been definitely linked to the death of a 65-year-old kidney dialysis patient who became ill during a blood cleaning process Nov 11. State Medical Examiner Dr. (illegible) Guard has ruled that Lawrence Blake, 65, of Arundel

  • Dental Fluorosis & Enamel Hypoplasia in Children with Kidney Disease

    Children with kidney disease are known to have high levels of fluoride in their blood and to be at risk for disfiguring tooth defects. Research suggests that high levels of fluoride in blood, which can cause the tooth defect known as dental fluorosis, can contribute to the defects that occur

  • Fluoride Content of Tea

    Tea, particularly tea drinks made with lower quality older leaves, contain high levels of fluoride. Because of these high levels, research has found that individuals who drink large amounts of tea can develop skeletal fluorosis -- a painful bone disease caused by excessive fluoride intake. Since skeletal fluorosis is often misdiagnosed by

  • Exposure Pathways Linked to Skeletal Fluorosis

    Excessive fluoride exposure from any source -- and from all sources combined -- can cause skeletal fluorosis. Some exposure pathways , however, have been specifically identified as placing individuals at risk of skeletal fluorosis. These exposure pathways include: Fluoridated Water for Kidney Patients Excessive Tea Consumption High-Fluoride Well Water Industrial Fluoride Exposure Fluorinated Pharmaceuticals (Voriconazole