Abstract
Rats receiving fluoride during the whole pregnancy up to the 9th day of lactation showed, when isolated at 10th day of life, a reduced rate of ultrasonic vocalizations (UV) in male pups (NaF 5.0 mg) and, in 90th days male rats, an increase of the Pre-Pulse Inhibition (PPI) with a reduction of the Peak response to the Startle stimulus given alone. Newborn rat reactivity could represent a useful and validated model in anxiety studies which could be moored with the Acoustic Startle Reflex (ASR) and PPI, appropriate models to study, in adulthood, particular neurological and psychiatric disorders showing deficits in attention and sensory-motor gating (Tourettes’ syndrome, obsessive compulsive disorders, Huntington’s disease and schizophrenia).
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Behavioral effects of chemicals in drinking water
Two experiments were conducted in order to determine if challenge testing, a procedure developed by clinical allergists, could be used to provoke behavioral reactions to chemicals found in municipal waters. In one experiment, 10 male and 32 female volunteers tracked a moving target and monitored lights after receiving sublingual drops that
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Effects of black tea in mitigation of sodium fluoride potency to suppress motor activity and coordination in laboratory rats
The present study was designed to assess the potential impact of Na-F alone or in conjugation with black tea on motor function and coordination performance in laboratory rats. An array of behavioural motor tasks, viz., open field, plank walking and rod walking tests were employed in our study in order
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Fluoride Exposure and Neurodevelopmental Outcomes Among Children in the United States: A pilot study.
Background/Aim: Developmental neurotoxicity of fluoride has been demonstrated in animal studies. Additionally, fluoride exposure during prenatal development, infancy, middle-to-late childhood and adolescence has been associated with poorer neurodevelopmental outcomes among children in Mexico and/or Canada. However, potential impacts of chronic low-level fluoride exposure in early childhood on brain structure and
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Investigation of the possible associations between fluorosis, fluoride exposure, and childhood behavior problems.
Purpose: This study investigated the potential association between fluoride exposure and behavior problems in children, as well as the prevalence of and risk factors for fluorosis. Methods: Children between the ages of 7 and 1 years (N = 197) were included in the study and were examined
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Fluoride exposure during pregnancy from a community water supply is associated with executive function in preschool children: A prospective ecological cohort study
Highlights Maternal fluoride exposure from drinking water was associated with executive function. Poorer inhibitory control and cognitive flexibility were found, particularly in girls. Maternal fluoride exposure was not associated with lower intelligence in children. Water fluoridated at the recommended level of 0.7 mg/L may adversely affect executive function. Background On May 19,
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NRC (2006): Fluoride's Neurotoxicity and Neurobehavioral Effects
The NRC's analysis on fluoride and the brain.
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Fluoride's Direct Effects on Brain: Animal Studies
The possibility that fluoride ingestion may impair intelligence and other indices of neurological function is supported by a vast body of animal research, including over 40 studies that have investigated fluoride's effects on brain quality in animals. As discussed by the National Research Council, the studies have consistently demonstrated that fluoride, at widely varying concentrations, is toxic to the brain.
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Fluoride: Developmental Neurotoxicity.
Developmental Neurotoxicity There has been a tremendous amount of research done on the association of exposure to fluoride with developmental neurotoxicity. There are 78 studies reporting reduced IQ (75 studies with children and 3 studies with adults) and several on the impaired learning/memory in animals. And there are studies which link
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Fluoride's Effect on Fetal Brain
The human placenta does not prevent the passage of fluoride from a pregnant mother's bloodstream to the fetus. As a result, a fetus can be harmed by fluoride ingested pregnancy. Based on research from China, the fetal brain is one of the organs susceptible to fluoride poisoning. As highlighted by the excerpts
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Fluoride Affects Learning & Memory in Animals
An association between elevated fluoride exposure and reduced intelligence has now been observed in 65 IQ studies. Although a link between fluoride and intelligence might initially seem surprising or random, it is actually consistent with a large body of animal research. This animal research includes the following 45 studies (out
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