Summary and Conclusions
Five cohorts totaling 2,509 children of the same age (7 years, 2 through 4 months), all with essentially the same postnatal exposure to optimally fluoridated water but with different patterns of prenatal exposure, were compared for prevalence of dental caries in their deciduous cuspids and molars and first permanent molars.
The data indicate that there were no meaningful additional benefits from the maternal ingestion of fluoridated water if the offspring also ingested the water from birth. The results cast serious doubts on the benefits to be derived from dietary supplements of fluoride to pregnant women.
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The amounts of fluoride in current fluoride therapies: safety considerations for children.
With the increased use of various fluoride preparations for caries prevention, all dental personnel should know their potential toxicity and the margins of safety associated with their use. An understanding of the body's mechanisms for handling fluoride provides a rational basis for assessing the possible risks of excessive fluoride ingestion.
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Fluoride Revolution and Dental Caries: Evolution of Policies for Global Use.
Epidemiological studies over 70 y ago provided the basis for the use of fluoride in caries prevention. They revealed the clear relation between water fluoride concentration, and therefore fluoride exposure, and prevalence and severity of dental fluorosis and dental caries. After successful trials, programs for water fluoridation were introduced, and
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A case-control study of topical and supplemental fluoride use and osteosarcoma risk.
Background: A relationship between fluoride and osteosarcoma has been hypothesized but not validated. To the authors’ knowledge, there are no published studies examining topical fluoride or dietary fluoride supplements and osteosarcoma risk. The purpose of this study was to examine the association between ever or never use of topical and
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Risk factors associated with fluorosis in a non-fluoridated population in Norway.
In Norway, there is no water fluoridation and little naturally occurring fluoride in drinking water. Fluoride toothpaste is used by 95% of the population and there is a long tradition of fluoride supplement use. The purpose of this study was to record the prevalence and severity of dental fluorosis in
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The Role of Fluoride in the Prevention of Tooth Decay
KEYWORDS • Dental caries • Dental decay • Oral health • Fluorides • Primary prevention • Secondary prevention • Children KEY POINTS • Fluoride is the key to prevention of tooth decay. • There are multiple fluoride modalities. • Effectiveness and safety of fluoride depend on dose and concentration. • Individual level
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Physician's Desk Reference: Fluoride Hypersensitivity
The following are excerpts from various editions of the Physicians' Desk Reference (PDR). "In hypersensitive individuals, fluorides occasionally cause skin eruptions such as atopic dermatitis, eczema or urticaria. Gastric distress, headache and weakness have also been reported. These hypersensitivity reactions usually disappear promptly after discontinuation of the fluoride. In rare cases,
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Prenatal and postnatal ingestion of fluorides - A progress report.
The cases described indicate that certain patients react unfavorably to fluoride therapy. Whether the fluorine acts as an allergen after short term use or whether the fluorine acts as an intoxicant after many months of use, is unknown and should be determined.
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Another Fluoride Fatality: A Physician's Dilemma
Why do physicians fail to correctly evaluate the toxicity of fluoride? Most textbooks rely on the now outdated views of Smith and Hodge who 25 years ago designated 5 to 10 g of fluoride the fatal toxic dose.
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Allergy to Fluoride
Six children and one adult exhibited various allergic reactions after the use of toothpaste and vitaimin preparations containing fluoride. The following conditions were encountered: Urticaria, exfoliative dermatitis, atopic dermatitis, stomatitis, gastro-intestinal and respiratory allergy.
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