Summary and Conclusions
Five cohorts totaling 2,509 children of the same age (7 years, 2 through 4 months), all with essentially the same postnatal exposure to optimally fluoridated water but with different patterns of prenatal exposure, were compared for prevalence of dental caries in their deciduous cuspids and molars and first permanent molars.
The data indicate that there were no meaningful additional benefits from the maternal ingestion of fluoridated water if the offspring also ingested the water from birth. The results cast serious doubts on the benefits to be derived from dietary supplements of fluoride to pregnant women.
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Placental transfer of fluoride in the human fetus at low and high F-intake.
In a previous investigation it was established that in pregnant women drinking water with a medium fluoride concentration, 0.5-0.6 ppm F, the mean F-value of the placenta is significantly higher than that in the cord blood or the maternal blood. The findings under such conditions suggest that the placenta accumulates
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Patterns of fluoride intake from 36 to 72 months of age
OBJECTIVES: This paper reports on estimated daily fluoride intake from water by itself, beverages, selected foods, dentifrice, and dietary supplements, both individually and combined (mg and mg F/kg bw), among 785 children in the Iowa Fluoride Study from 36 to 72 months of age. METHODS: Children were recruited in 1992-95,
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Risk of enamel fluorosis associated with fluoride supplementation, infant formula, and fluoride dentifrice use.
Eight hundred fifty 11- to 14-year-old residents of nonfluoridated communities in Massachusetts and Connecticut, who were born between 1972 and 1975, were investigated in a case-control study of the possible association between enamel fluorosis and exposure to fluoride supplements, infant formula, and/or fluoride dentifrice. The effect of median household income,
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The prevalence and risk factors of fluorosis among patients in a pediatric dental practice
Seven hundred eight patients aged 5-19 years in a pediatric practice in North Carolina were selected using a random-start, systematic sampling procedure and enrolled in a case control study to determine risks for fluorosis. Subjects were examined by four trained examiners using the Tooth Surface Index of Fluorosis (TSIF). Information
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Knowledge and Attitudes Towards Fluoride Supplementation: A Survey of Pediatric Medical and Dental Providers in the State of Hawai'i.
Hawai'i has the lowest rate of community water fluoridation in the nation, which has contributed to poor oral health for children statewide. When properly prescribed, the benefits of fluoride supplementation for oral health outweigh any potential side effects to the body. Official recommendations give pediatric healthcare providers the authority to
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Physician's Desk Reference: Fluoride Hypersensitivity
The following are excerpts from various editions of the Physicians' Desk Reference (PDR). "In hypersensitive individuals, fluorides occasionally cause skin eruptions such as atopic dermatitis, eczema or urticaria. Gastric distress, headache and weakness have also been reported. These hypersensitivity reactions usually disappear promptly after discontinuation of the fluoride. In rare cases,
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Allergy to Fluoride
Six children and one adult exhibited various allergic reactions after the use of toothpaste and vitaimin preparations containing fluoride. The following conditions were encountered: Urticaria, exfoliative dermatitis, atopic dermatitis, stomatitis, gastro-intestinal and respiratory allergy.
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Prenatal and postnatal ingestion of fluorides - A progress report.
The cases described indicate that certain patients react unfavorably to fluoride therapy. Whether the fluorine acts as an allergen after short term use or whether the fluorine acts as an intoxicant after many months of use, is unknown and should be determined.
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Another Fluoride Fatality: A Physician's Dilemma
Why do physicians fail to correctly evaluate the toxicity of fluoride? Most textbooks rely on the now outdated views of Smith and Hodge who 25 years ago designated 5 to 10 g of fluoride the fatal toxic dose.
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