Summary and Conclusions
Five cohorts totaling 2,509 children of the same age (7 years, 2 through 4 months), all with essentially the same postnatal exposure to optimally fluoridated water but with different patterns of prenatal exposure, were compared for prevalence of dental caries in their deciduous cuspids and molars and first permanent molars.
The data indicate that there were no meaningful additional benefits from the maternal ingestion of fluoridated water if the offspring also ingested the water from birth. The results cast serious doubts on the benefits to be derived from dietary supplements of fluoride to pregnant women.
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Placental transfer of fluoride in the human fetus at low and high F-intake.
In a previous investigation it was established that in pregnant women drinking water with a medium fluoride concentration, 0.5-0.6 ppm F, the mean F-value of the placenta is significantly higher than that in the cord blood or the maternal blood. The findings under such conditions suggest that the placenta accumulates
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Filled dietary fluoride supplement prescriptions for Medicaid-enrolled children living in states with high and low water fluoridation coverage.
BACKGROUND: Although dietary fluoride (F) supplements (DFS) are recommended for children who use F-deficient drinking water, no studies have examined filled DFS prescriptions across multiple states to examine the dosage consistency with current recommendations or prescription length. METHODS: This sequential cross-sectional analysis used Medicaid claims data for children aged 0.5 through
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No evidence that fluoride supplements taken during pregnancy prevent caries.
Data sources: Cochrane Oral Healths Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL) Medline, Embase, LILACS BIREME Virtual Health Library CINAHL US National Institutes of Health Ongoing Trials Register (ClinicalTrials.gov) and the World Health Organization International Clinical Trials Registry Platform databases. Study selection: Randomised controlled trials (RCTs) including quasi-randomised
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Patterns of fluoride intake from 36 to 72 months of age
OBJECTIVES: This paper reports on estimated daily fluoride intake from water by itself, beverages, selected foods, dentifrice, and dietary supplements, both individually and combined (mg and mg F/kg bw), among 785 children in the Iowa Fluoride Study from 36 to 72 months of age. METHODS: Children were recruited in 1992-95,
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Effects of fluoride supplementation from birth on human deciduous and permanent teeth.
A group (I) of 7–12-yr-old children from non-fluoridated communities who had ingested 0.5 mg F supplement/day from shortly after birth to the age of 3 yr. and 1 mg/day thereafter was compared with a control group (II) from the same communities and with a group (III) with lifetime exposure to
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Physician's Desk Reference: Fluoride Hypersensitivity
The following are excerpts from various editions of the Physicians' Desk Reference (PDR). "In hypersensitive individuals, fluorides occasionally cause skin eruptions such as atopic dermatitis, eczema or urticaria. Gastric distress, headache and weakness have also been reported. These hypersensitivity reactions usually disappear promptly after discontinuation of the fluoride. In rare cases,
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Prenatal and postnatal ingestion of fluorides - A progress report.
The cases described indicate that certain patients react unfavorably to fluoride therapy. Whether the fluorine acts as an allergen after short term use or whether the fluorine acts as an intoxicant after many months of use, is unknown and should be determined.
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Allergy to Fluoride
Six children and one adult exhibited various allergic reactions after the use of toothpaste and vitaimin preparations containing fluoride. The following conditions were encountered: Urticaria, exfoliative dermatitis, atopic dermatitis, stomatitis, gastro-intestinal and respiratory allergy.
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Another Fluoride Fatality: A Physician's Dilemma
Why do physicians fail to correctly evaluate the toxicity of fluoride? Most textbooks rely on the now outdated views of Smith and Hodge who 25 years ago designated 5 to 10 g of fluoride the fatal toxic dose.
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