Summary and Conclusions
Five cohorts totaling 2,509 children of the same age (7 years, 2 through 4 months), all with essentially the same postnatal exposure to optimally fluoridated water but with different patterns of prenatal exposure, were compared for prevalence of dental caries in their deciduous cuspids and molars and first permanent molars.
The data indicate that there were no meaningful additional benefits from the maternal ingestion of fluoridated water if the offspring also ingested the water from birth. The results cast serious doubts on the benefits to be derived from dietary supplements of fluoride to pregnant women.
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The amounts of fluoride in current fluoride therapies: safety considerations for children.
With the increased use of various fluoride preparations for caries prevention, all dental personnel should know their potential toxicity and the margins of safety associated with their use. An understanding of the body's mechanisms for handling fluoride provides a rational basis for assessing the possible risks of excessive fluoride ingestion.
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Fluoride and Oral Health.
In 1993, the World Health Organization convened an Expert Committee to provide authoritative information on the role of fluorides in the promotion of oral health throughout the world (WHO TRS 846, 1994). This present publication is a revision of the original 1994 document, again using the expertise of researchers from
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Fluoride metabolism and fluorosis.
OBJECTIVES: This paper is primarily concerned with the only proven risk associated with water fluoridation: enamel fluorosis. Its purpose is to review current methods of measuring enamel fluorosis, its aetiology and metabolism. A further objective is to identify risk factors to reduce the prevalence of enamel fluorosis and employ methods
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A quantitative look at fluorosis, fluoride exposure, and intake in children using a health risk assessment approach
The prevalence of dental fluorosis in the United States has increased during the last 30 years. In this study, we used a mathematical model commonly employed by the U.S. Environmental Protection Agency to estimate average daily intake offluoride via all applicable exposure pathways contributing to fluorosis risk for infants and children
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Risk of enamel fluorosis associated with fluoride supplementation, infant formula, and fluoride dentifrice use.
Eight hundred fifty 11- to 14-year-old residents of nonfluoridated communities in Massachusetts and Connecticut, who were born between 1972 and 1975, were investigated in a case-control study of the possible association between enamel fluorosis and exposure to fluoride supplements, infant formula, and/or fluoride dentifrice. The effect of median household income,
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Prenatal and postnatal ingestion of fluorides - A progress report.
The cases described indicate that certain patients react unfavorably to fluoride therapy. Whether the fluorine acts as an allergen after short term use or whether the fluorine acts as an intoxicant after many months of use, is unknown and should be determined.
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Another Fluoride Fatality: A Physician's Dilemma
Why do physicians fail to correctly evaluate the toxicity of fluoride? Most textbooks rely on the now outdated views of Smith and Hodge who 25 years ago designated 5 to 10 g of fluoride the fatal toxic dose.
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Physician's Desk Reference: Fluoride Hypersensitivity
The following are excerpts from various editions of the Physicians' Desk Reference (PDR). "In hypersensitive individuals, fluorides occasionally cause skin eruptions such as atopic dermatitis, eczema or urticaria. Gastric distress, headache and weakness have also been reported. These hypersensitivity reactions usually disappear promptly after discontinuation of the fluoride. In rare cases,
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Allergy to Fluoride
Six children and one adult exhibited various allergic reactions after the use of toothpaste and vitaimin preparations containing fluoride. The following conditions were encountered: Urticaria, exfoliative dermatitis, atopic dermatitis, stomatitis, gastro-intestinal and respiratory allergy.
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