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  • Fluoride and Biological Calcification I: Effect of Fluoride on Collagen-Induced In Vitro Mineralization and Demineralization Reactions.

    References Glimcher MJ (1959) Molecular biology of mineralized tissues with particular reference to bone. Rev Mod Phys 31:359–393. https://doi.org/10.1103/RevModPhys.31.359 CAS  Article  Google Scholar Cheng P-T (1985) Octacalcium phosphate formationin vitro: implications for bone formation. Calcif Tissue Int 37:91–94. https://doi.org/10.1007/BF02557685 CAS  Article  PubMed  Google Scholar Cadet ER, Gafni RI, Mccarthy EF, Mccray DR, Bacher JD, Barnes […]

  • Prevalence and estimation of the occupational risk of the musculoskeletal disorders in workers of aluminum potrooms

    The most severe consequence of intensive exposure to fluorides is skeletal injury with initial injury of spongy bones (pelvis and spine) and calcification of the ligaments, followed by involvement of the long bones in the disease. These radiological-morphological abnormalities are the diagnostic criteria and have been made the basis for classification of skeletal fluorosis [5, […]

  • Fluoride-induced apoptosis in non-skeletal tissues of experimental animals: A systematic review and meta-analysis.

    1. Introduction … Apoptosis is a highly regulated and programmed cell death characterized by specific biochemical and morphological features that culminate in cellular shrinkage to apoptotic bodies that are engulfed by neighboring macrophages [[12]]. This occurs without an accompanying inflammatory response. Characterized morphological changes accompanying apoptosis include cleavage of cytoskeletal filament fibers, cell cytoplasm, and […]

  • Neuroligin-3 activates Akt-dependent Nrf2 cascade to protect osteoblasts from oxidative stress.

    Introduction Osteoblasts are derived from mesenchymal progenitor cells and are the main functional cells for bone formation [[1], [2], [3]]. They are responsible for the synthesis, secretion and mineralization of bone matrix and can secrete various bioactive substances for bone formation and reconstruction [[1], [2], [3]]. In the pathogenesis of osteoporosis, uncontrolled reactive oxygen species […]

  • X-ray diagnosis of fluorine-associated arthropathy

    I. Pathological basis and X-ray signs of fluorine-associated arthropathy Long-term uptake of excessive fluorine may cause pathological changes of bone structure and bone periphery; furthermore, animal experiments and epidemiological investigations demonstrate that fluorosis may cause necrosis, degeneration and ulceration of articular cartilage, and also cause necrosis of subchondral bones, leading to hypertrophy of synovium and […]

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  • Fluoridegate bombshell

    • Documents Show Officials’ Efforts to Control News of Water Fluoridation Harm to African Americans • Black Pastors Group President, Erin Brockovich, Others Call for Fluoridegate Hearing Federal health officials, in close communication with dental industry representatives, worked feverishly to blunt spread of news that African Americans are disproportionately harmed by drinking fluoridated water, according […]

  • The effect of small quantities of fluorine on the human body

    Based on several studies, national standard GOST 2874-54 established the maximum allowable concentration of fluorine in drinking water to be 1.5 mg/l. However, this standard cannot be considered sufficiently substantiated. Despite the fact that fluorine exhibits strong neurotropic activity, the question pertaining to the functional state of the nervous system as a result of the […]

  • Role of fluoride in formation of urinary calculi: studies in rats.

  • Regional and racial/ethnic inequalities in public drinking water fluoride concentrations across the US.

    References  Articles referenced by this article (26) Water fluoridation for the prevention of dental caries. Iheozor-Ejiofor Z, Worthington HV, Walsh T, O’Malley L, Clarkson JE, Macey R, Alam R, Tugwell P, Welch V, Glenny AM Cochrane Database Syst Rev, (6):CD010856 2015 MED: 26092033 The effectiveness of community water fluoridation in the United States. Horowitz HS […]