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A Systematic Review and Meta-Analysis of the Relationship Between the Severity of Dental Fluorosis and Fluoride Biomarkers in Endemic Areas.
References Wei W, Pang S, Sun D (2019) The pathogenesis of endemic fluorosis: Research progress in the last 5 years. J Cell Mol Med 23:2333–2342. https://doi.org/10.1111/jcmm.14185 CAS Article PubMed PubMed Central Google Scholar Patil MM, Lakhkar BB, Patil SS (2018) Curse of Fluorosis. Indian J Pediatr 85:375–383. https://doi.org/10.1007/s12098-017-2574-z CAS Article PubMed Google Scholar Kurdi MS […]
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Early diagnosis and classification of professional fluorosis
Diagnosis of professional fluorosis (PF) and its classification have been poorly studied. After development of PF classification by D. M. Zislin and E. Ya. Girskaya [3], new study methods have been introduced in clinical practice which have allowed some indications of the disease to be revealed [2, 5, 6, 8]. However, this classification does not […]
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Environmental exposures and pediatric kidney function and disease: A systematic review.
Two studies investigated the association of fluoride exposure, including 1 cross-sectional and 1 case-control. In a cross-sectional study of fluoride exposure in 210 children in China, the investigators found increases of urine NAG and urine ?-GT levels (Liu et al., 2005). In case-control study of fluoride levels in 210 children in China, slightly higher urine […]
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Effect of fluoride on bone formation and strength in Japanese quail
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WITHDRAWN: Community-based population-level interventions for promoting child oral health.
Discussion Summary of main results This review includes 38 studies of community-based population-level interventions for promoting child oral health, with a total of 119,789 children. Interventions were generally implemented for less than one year (n = 26), and about half (n = 11) of studies were randomised controlled trials. Investigators tested a variety of oral […]
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Dopamine receptor D2 gene polymorphism, urine fluoride, and intelligence impairment of children in China: A school-based cross-sectional study.
EXCERPTS … In China, endemic fluorosis is classified into drinking-water type, drinking-tea type, and coal-burning type. Humans are exposed to high fluoride mainly through drinking groundwater with high fluoride content (Barbier et al., 2010). When fluorine is absorbed, it enters the blood and distributes throughout the body, mainly in bones and teeth (Barbier et al., […]
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Biomimetic hydroxyapatite and caries prevention: a systematic review and meta-analysis.
For decades, fluoride has been the pre-eminent ingredient in consumer products to prevent dental caries. The evidence that fluoridated toothpaste significantly reduces caries is well documented. 8 , 9 It is now widely accepted that fluoride prevents dental decay by encouraging topical remineralization of early white spot, incipient lesions. New non-fluoride remineralization strategies have emerged […]
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Progress of Signaling Pathways, Stress Pathways and Epigenetics in the Pathogenesis of Skeletal Fluorosis.
1. Introduction Fluorine is one of the most common halogens, which usually exists in the environment as compounds. Fluorine or fluoride enters the human body primarily through drinking water, food, and air. Once absorbed into the bloodstream, it is easily transported throughout the body in the form of ions. More than 90% of absorbed fluoride […]
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Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses.
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Studies on alterations in brain lipid metabolism following experimental fluorosis